PDB entry 2y0b

View 2y0b on RCSB PDB site
Description: caspase-3 in complex with an inhibitory darpin-3.4_s76r
Deposited on 2010-12-01, released 2011-12-21
The last revision was dated 2019-02-20, with a file datestamp of 2019-02-15.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: caspase-3 subunit p17
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Caspase-3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: caspase-3 subunit p17
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Caspase-3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: darpin-3.4_s76r
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 2Y0B
  • Chain 'H':
    Compound: darpin-3.4_s76r
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 2Y0B
  • Heterogens: MPD, MRD, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2y0bA (A:)
mssgisldnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevr
nkndltreeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgd
rcrsltgkpklfiiqacrgteldcgietd

    Sequence, based on observed residues (ATOM records):
    >2y0bA (A:)
dnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnkndltr
eeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrcrsltg
kpklfiiqacrgteldcgiet

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2y0bB (B:)
sgvdddmachkipveadflyaystapgyyswrnskdgswfiqslcamlkqyadklefmhi
ltrvnrkvatefesfsfdatfhakkqipcivsmltkelyfyhalevlfqgphhhhhhh

    Sequence, based on observed residues (ATOM records):
    >2y0bB (B:)
chkipveadflyaystapgyyswrnskdgswfiqslcamlkqyadklefmhiltrvnrkv
atefesfsfdatfhakkqipcivsmltkelyfyh

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2y0bC (C:)
mssgisldnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevr
nkndltreeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgd
rcrsltgkpklfiiqacrgteldcgietd

    Sequence, based on observed residues (ATOM records):
    >2y0bC (C:)
dnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnkndltr
eeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrcrsltg
kpklfiiqacrgteldcgiet

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2y0bD (D:)
sgvdddmachkipveadflyaystapgyyswrnskdgswfiqslcamlkqyadklefmhi
ltrvnrkvatefesfsfdatfhakkqipcivsmltkelyfyhalevlfqgphhhhhhh

    Sequence, based on observed residues (ATOM records):
    >2y0bD (D:)
hkipveadflyaystapgyyswrnskdgswfiqslcamlkqyadklefmhiltrvnrkva
tefesfsfdatfhakkqipcivsmltkelyfyh

  • Chain 'G':
    Sequence, based on SEQRES records:
    >2y0bG (G:)
mrgshhhhhhgsdlgkklleatragqddevrilmangadvnamddagvtplhlaakrghl
eivevllkhgadvnardiwgrtplhlaatvghleivevlleygadvnaqdkfgktafdis
idngnedlaeilqkln

    Sequence, based on observed residues (ATOM records):
    >2y0bG (G:)
dlgkklleatragqddevrilmangadvnamddagvtplhlaakrghleivevllkhgad
vnardiwgrtplhlaatvghleivevlleygadvnaqdkfgktafdisidngnedlaei

  • Chain 'H':
    Sequence, based on SEQRES records:
    >2y0bH (H:)
mrgshhhhhhgsdlgkklleatragqddevrilmangadvnamddagvtplhlaakrghl
eivevllkhgadvnardiwgrtplhlaatvghleivevlleygadvnaqdkfgktafdis
idngnedlaeilqkln

    Sequence, based on observed residues (ATOM records):
    >2y0bH (H:)
dlgkklleatragqddevrilmangadvnamddagvtplhlaakrghleivevllkhgad
vnardiwgrtplhlaatvghleivevlleygadvnaqdkfgktafdisidngnedlaeil