PDB entry 2y05

View 2y05 on RCSB PDB site
Description: crystal structure of human leukotriene b4 12-hydroxydehydrogenase in complex with nadp and raloxifene
Deposited on 2010-11-30, released 2011-01-26
The last revision was dated 2018-01-24, with a file datestamp of 2018-01-19.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: prostaglandin reductase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q14914 (2-327)
      • expression tag (0-1)
      • variant (25)
  • Chain 'B':
    Compound: prostaglandin reductase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q14914 (2-327)
      • expression tag (0-1)
      • variant (25)
  • Chain 'C':
    Compound: prostaglandin reductase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q14914 (2-327)
      • expression tag (0-1)
      • variant (25)
  • Chain 'D':
    Compound: prostaglandin reductase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q14914 (2-327)
      • expression tag (0-1)
      • variant (25)
  • Heterogens: NAP, RAL, CL, EDO, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >2y05A (A:)
smtktwtlkkhfvgyptnsdfelktselpplkngevllealfltvdpymrvaakrlkegd
tmmgqqvakvvesknvalpkgtivlaspgwtthsisdgkdleklltewpdtiplslalgt
vgmpgltayfglleicgvkggetvmvnaaagavgsvvgqiaklkgckvvgavgsdekvay
lqklgfdvvfnyktvesleetlkkaspdgydcyfdnvggefsntvigqmkkfgriaicga
istynrtgplppgpppeiviyqelrmeafvvyrwqgdarqkalkdllkwvlegkiqykey
iiegfenmpaafmgmlkgdnlgktivka

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >2y05B (B:)
smtktwtlkkhfvgyptnsdfelktselpplkngevllealfltvdpymrvaakrlkegd
tmmgqqvakvvesknvalpkgtivlaspgwtthsisdgkdleklltewpdtiplslalgt
vgmpgltayfglleicgvkggetvmvnaaagavgsvvgqiaklkgckvvgavgsdekvay
lqklgfdvvfnyktvesleetlkkaspdgydcyfdnvggefsntvigqmkkfgriaicga
istynrtgplppgpppeiviyqelrmeafvvyrwqgdarqkalkdllkwvlegkiqykey
iiegfenmpaafmgmlkgdnlgktivka

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >2y05C (C:)
smtktwtlkkhfvgyptnsdfelktselpplkngevllealfltvdpymrvaakrlkegd
tmmgqqvakvvesknvalpkgtivlaspgwtthsisdgkdleklltewpdtiplslalgt
vgmpgltayfglleicgvkggetvmvnaaagavgsvvgqiaklkgckvvgavgsdekvay
lqklgfdvvfnyktvesleetlkkaspdgydcyfdnvggefsntvigqmkkfgriaicga
istynrtgplppgpppeiviyqelrmeafvvyrwqgdarqkalkdllkwvlegkiqykey
iiegfenmpaafmgmlkgdnlgktivka

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >2y05D (D:)
smtktwtlkkhfvgyptnsdfelktselpplkngevllealfltvdpymrvaakrlkegd
tmmgqqvakvvesknvalpkgtivlaspgwtthsisdgkdleklltewpdtiplslalgt
vgmpgltayfglleicgvkggetvmvnaaagavgsvvgqiaklkgckvvgavgsdekvay
lqklgfdvvfnyktvesleetlkkaspdgydcyfdnvggefsntvigqmkkfgriaicga
istynrtgplppgpppeiviyqelrmeafvvyrwqgdarqkalkdllkwvlegkiqykey
iiegfenmpaafmgmlkgdnlgktivka