PDB entry 2xzd

View 2xzd on RCSB PDB site
Description: Caspase-3 in Complex with an Inhibitory DARPin-3.4
Deposited on 2010-11-24, released 2011-12-14
The last revision was dated 2013-02-20, with a file datestamp of 2013-02-15.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.18667
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Caspase-3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Caspase-3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Caspase-3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Caspase-3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: darpin-3.4
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 2XZD
  • Chain 'H':
    Compound: darpin-3.4
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 2XZD
  • Heterogens: MRD, MPD, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2xzdA (A:)
mssgisldnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevr
nkndltreeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgd
rcrsltgkpklfiiqacrgteldcgietd

    Sequence, based on observed residues (ATOM records):
    >2xzdA (A:)
dnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnkndltr
eeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrcrsltg
kpklfiiqacrgteldcgiet

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2xzdB (B:)
sgvdddmachkipveadflyaystapgyyswrnskdgswfiqslcamlkqyadklefmhi
ltrvnrkvatefesfsfdatfhakkqipcivsmltkelyfyhalevlfqgphhhhhhh

    Sequence, based on observed residues (ATOM records):
    >2xzdB (B:)
chkipveadflyaystapgyyswrnskdgswfiqslcamlkqyadklefmhiltrvnrkv
atefesfsfdatfhakkqipcivsmltkelyfyh

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2xzdC (C:)
mssgisldnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevr
nkndltreeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgd
rcrsltgkpklfiiqacrgteldcgietd

    Sequence, based on observed residues (ATOM records):
    >2xzdC (C:)
dnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnkndltr
eeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrcrsltg
kpklfiiqacrgteldcgietd

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2xzdD (D:)
sgvdddmachkipveadflyaystapgyyswrnskdgswfiqslcamlkqyadklefmhi
ltrvnrkvatefesfsfdatfhakkqipcivsmltkelyfyhalevlfqgphhhhhhh

    Sequence, based on observed residues (ATOM records):
    >2xzdD (D:)
hkipveadflyaystapgyyswrnskdgswfiqslcamlkqyadklefmhiltrvnrkva
tefesfsfdatfhakkqipcivsmltkelyfyh

  • Chain 'G':
    Sequence, based on SEQRES records:
    >2xzdG (G:)
mrgshhhhhhgsdlgkklleatragqddevrilmangadvnamddagvtplhlaakrghl
eivevllkhgadvnasdiwgrtplhlaatvghleivevlleygadvnaqdkfgktafdis
idngnedlaeilqkln

    Sequence, based on observed residues (ATOM records):
    >2xzdG (G:)
dlgkklleatragqddevrilmangadvnamddagvtplhlaakrghleivevllkhgad
vnasdiwgrtplhlaatvghleivevlleygadvnaqdkfgktafdisidngnedlaei

  • Chain 'H':
    Sequence, based on SEQRES records:
    >2xzdH (H:)
mrgshhhhhhgsdlgkklleatragqddevrilmangadvnamddagvtplhlaakrghl
eivevllkhgadvnasdiwgrtplhlaatvghleivevlleygadvnaqdkfgktafdis
idngnedlaeilqkln

    Sequence, based on observed residues (ATOM records):
    >2xzdH (H:)
dlgkklleatragqddevrilmangadvnamddagvtplhlaakrghleivevllkhgad
vnasdiwgrtplhlaatvghleivevlleygadvnaqdkfgktafdisidngnedlaeil