PDB entry 2xym

View 2xym on RCSB PDB site
Description: hcv-jfh1 ns5b t385a mutant
Class: transferase
Keywords: transferase, hepacivirus, nonstructural proteins, replication, de novo initiation, priming
Deposited on 2010-11-18, released 2011-01-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-04-06, with a file datestamp of 2011-04-01.
Experiment type: XRAY
Resolution: 1.77 Å
R-factor: 0.1813
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: RNA-directed RNA polymerase
    Species: HEPATITIS C VIRUS [TaxId:356411]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99IB8 (0-562)
      • engineered mutation (384)
    Domains in SCOPe 2.08: d2xyma_
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2xymA (A:)
smsyswtgalitpcspeeeklpinplsnsllryhnkvycttsksasqrakkvtfdrtqvl
dahydsvlkdiklaaskvsarlltleeacqltpphsarskygfgakevrslsgravnhik
svwkdlledpqtpipttimaknevfcvdpakggkkparlivypdlgvrvcekmalyditq
klpqavmgasygfqyspaqrveyllkawaekkdpmgfsydtrcfdstvterdirteesiy
qacslpeeartaihslterlyvggpmfnskgqtcgyrrcrasgvlttsmgntitcyvkal
aackaagivaptmlvcgddlvvisesqgteedernlrafteamtrysappgdpprpeydl
elitscssnvsvalgprgrrryylardpttplaraawetvrhspinswlgniiqyaptiw
vrmvlmthffsilmvqdtldqnlnfemygsvysvnpldlpaiierlhgldafsmhtyshh
eltrvasalrklgapplrvwksraravraslisrggkaavcgrylfnwavktklkltplp
earlldlsswftvgagggdifhs