PDB entry 2xx3

View 2xx3 on RCSB PDB site
Description: human thymidylate kinase complexed with thymidine butenyl phosphonate monophosphate and ADP
Class: transferase
Keywords: transferase, acyclic nucleoside phosphonate
Deposited on 2010-11-08, released 2011-12-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-12-07, with a file datestamp of 2011-12-02.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.1911
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thymidylate kinase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2xx3a_
  • Heterogens: ADP, MG, TAE, NO3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2xx3A (A:)
mgsshhhhhhssglvprgshmaarrgalivlegvdragkstqsrklvealcaaghraell
rfpersteigkllssylqkksdvedhsvhllfsanrweqvplikeklsqgvtlvvdryaf
sgvaftgakenfsldwckqpdvglpkpdlvlflqlqladaakrgafgheryengafqera
lrcfhqlmkdttlnwkmvdasksieavhedirvlsedairtatekplgelwk

    Sequence, based on observed residues (ATOM records): (download) 
    >2xx3A (A:)
arrgalivlegvdragkstqsrklvealcahraellrfpersteigkllsvedhsvhllf
sanrweqvplikeklsqgvtlvvdryafsgvaftgakenfsldwckqpdvglpkpdlvlf
lqlqladaakrgafgheryengafqeralrcfhqlmkdttlnwkmvdasksieavhedir
vlsedairtatekplgelwk