SCOPe 2.08: Structural Classification of Proteins

PDB entry 2xsh

View 2xsh on RCSB PDB site
Description: crystal structure of p4 variant of biphenyl dioxygenase from burkholderia xenovorans lb400 in complex with 2,6 di chlorobiphenyl
Class: oxidoreductase
Keywords: oxidoreductase
Deposited on 2010-09-29, released 2010-11-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-02-16, with a file datestamp of 2011-02-11.
Experiment type: XRAY
Resolution: 2.29 Å
R-factor: 0.18863
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Biphenyl dioxygenase subunit alpha
Species: BURKHOLDERIA XENOVORANS [TaxId:266265]
Database cross-references and differences (RAF-indexed):
- Uniprot P37333 (Start-458)
  - engineered mutation (334-335)
Domains in SCOPe 2.08: d2xsha1, d2xsha2
Chain 'B':
Compound: Biphenyl dioxygenase subunit beta
Species: BURKHOLDERIA XENOVORANS [TaxId:266265]
Database cross-references and differences (RAF-indexed):
- Uniprot P37334 (Start-187)
Domains in SCOPe 2.08: d2xshb_
Chain 'C':
Compound: Biphenyl dioxygenase subunit alpha
Species: BURKHOLDERIA XENOVORANS [TaxId:266265]
Database cross-references and differences (RAF-indexed):
- Uniprot P37333 (Start-458)
  - engineered mutation (334-335)
Domains in SCOPe 2.08: d2xshc1, d2xshc2
Chain 'D':
Compound: Biphenyl dioxygenase subunit beta
Species: BURKHOLDERIA XENOVORANS [TaxId:266265]
Database cross-references and differences (RAF-indexed):
- Uniprot P37334 (Start-187)
Domains in SCOPe 2.08: d2xshd_
Chain 'E':
Compound: Biphenyl dioxygenase subunit alpha
Species: BURKHOLDERIA XENOVORANS [TaxId:266265]
Database cross-references and differences (RAF-indexed):
- Uniprot P37333 (Start-458)
  - engineered mutation (334-335)
Domains in SCOPe 2.08: d2xshe1, d2xshe2
Chain 'F':
Compound: Biphenyl dioxygenase subunit beta
Species: BURKHOLDERIA XENOVORANS [TaxId:266265]
Database cross-references and differences (RAF-indexed):
- Uniprot P37334 (Start-187)
Domains in SCOPe 2.08: d2xshf_
Chain 'G':
Compound: Biphenyl dioxygenase subunit alpha
Species: BURKHOLDERIA XENOVORANS [TaxId:266265]
Database cross-references and differences (RAF-indexed):
- Uniprot P37333 (Start-458)
  - engineered mutation (334-335)
Domains in SCOPe 2.08: d2xshg1, d2xshg2
Chain 'H':
Compound: Biphenyl dioxygenase subunit beta
Species: BURKHOLDERIA XENOVORANS [TaxId:266265]
Database cross-references and differences (RAF-indexed):
- Uniprot P37334 (Start-187)
Domains in SCOPe 2.08: d2xshh_
Chain 'I':
Compound: Biphenyl dioxygenase subunit alpha
Species: BURKHOLDERIA XENOVORANS [TaxId:266265]
Database cross-references and differences (RAF-indexed):
- Uniprot P37333 (Start-458)
  - engineered mutation (334-335)
Domains in SCOPe 2.08: d2xshi1, d2xshi2
Chain 'J':
Compound: Biphenyl dioxygenase subunit beta
Species: BURKHOLDERIA XENOVORANS [TaxId:266265]
Database cross-references and differences (RAF-indexed):
- Uniprot P37334 (Start-187)
Domains in SCOPe 2.08: d2xshj_
Chain 'K':
Compound: Biphenyl dioxygenase subunit alpha
Species: BURKHOLDERIA XENOVORANS [TaxId:266265]
Database cross-references and differences (RAF-indexed):
- Uniprot P37333 (Start-458)
  - engineered mutation (334-335)
Domains in SCOPe 2.08: d2xshk1, d2xshk2
Chain 'L':
Compound: Biphenyl dioxygenase subunit beta
Species: BURKHOLDERIA XENOVORANS [TaxId:266265]
Database cross-references and differences (RAF-indexed):
- Uniprot P37334 (Start-187)
Domains in SCOPe 2.08: d2xshl_
Heterogens: FES, FE2, DC5, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>2xshA (A:)
mssaikevqgapvkwvtnwtpeairglvdqekglldpriyadqslyelelervfgrswll
lgheshvpetgdflatymgedpvvmvrqkdksikvflnqcrhrgmricrsdagnakaftc
syhgwaydiagklvnvpfekeafcdkkegdcgfdkaewgplqarvatykglvfanwdvqa
pdletylgdarpymdvmldrtpagtvaiggmqkwvipcnwkfaaeqfcsdmyhagttthl
sgilagippemdlsqaqiptkgnqfraawgghgsgwyvdepgsllavmgpkvtqywtegp
aaelaeqrlghtgmpvrrmvgqhmtifptcsflpamnniriwhprgpneievwaftlvda
dapaeikeeyrrhnirnfsaggvfeqddgenwveiqkglrgykaksqplnaqmglgrsqt
ghpdfpgnvgyvyaeeaargmyhhwmrmmsepswatlkp