PDB entry 2xrs

View 2xrs on RCSB PDB site
Description: Crystal structures exploring the origins of the broader specificity of escherichia coli heat-labile enterotoxin compared to cholera toxin
Class: toxin
Keywords: toxin, host-pathogen interactions, molecular recognition, protein-carbohydrate interaction
Deposited on 2010-09-20, released 2010-12-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 1.81 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'D':
  Compound: heat-labile enterotoxin b chain
  Species: Escherichia coli [TaxId:562]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P32890 (0-102)
  Domains in SCOPe 2.08: d2xrsd_
• Chain 'E':
  Compound: heat-labile enterotoxin b chain
  Species: Escherichia coli [TaxId:562]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P32890 (0-102)
  Domains in SCOPe 2.08: d2xrse_
• Chain 'F':
  Compound: heat-labile enterotoxin b chain
  Species: Escherichia coli [TaxId:562]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P32890 (0-102)
  Domains in SCOPe 2.08: d2xrsf_
• Chain 'G':
  Compound: heat-labile enterotoxin b chain
  Species: Escherichia coli [TaxId:562]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P32890 (0-102)
  Domains in SCOPe 2.08: d2xrsg_
• Chain 'H':
  Compound: heat-labile enterotoxin b chain
  Species: Escherichia coli [TaxId:562]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P32890 (0-102)
  Domains in SCOPe 2.08: d2xrsh_
• Chain 'L':
  Compound: heat-labile enterotoxin b chain
  Species: Escherichia coli [TaxId:562]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P32890 (0-102)
  Domains in SCOPe 2.08: d2xrsl_
• Chain 'M':
  Compound: heat-labile enterotoxin b chain
  Species: Escherichia coli [TaxId:562]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P32890 (0-102)
  Domains in SCOPe 2.08: d2xrsm_
• Chain 'N':
  Compound: heat-labile enterotoxin b chain
  Species: Escherichia coli [TaxId:562]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P32890 (0-102)
  Domains in SCOPe 2.08: d2xrsn_
• Chain 'O':
  Compound: heat-labile enterotoxin b chain
  Species: Escherichia coli [TaxId:562]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P32890 (0-102)
  Domains in SCOPe 2.08: d2xrso_
• Chain 'P':
  Compound: heat-labile enterotoxin b chain
  Species: Escherichia coli [TaxId:562]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P32890 (0-102)
  Domains in SCOPe 2.08: d2xrsp_
• Heterogens: GAL, HOH

PDB Chain Sequences:

• Chain 'D':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2xrsD (D:)
  apqtitelcseyrntqiytindkilsytesmagkremviitfksgetfqvevpgsqhids
  qkkaiermkdtlrityltetkidklcvwnnktpnsiaaismkn
  

  
  
• Chain 'E':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2xrsE (E:)
  apqtitelcseyrntqiytindkilsytesmagkremviitfksgetfqvevpgsqhids
  qkkaiermkdtlrityltetkidklcvwnnktpnsiaaismkn
  

  
  
• Chain 'F':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2xrsF (F:)
  apqtitelcseyrntqiytindkilsytesmagkremviitfksgetfqvevpgsqhids
  qkkaiermkdtlrityltetkidklcvwnnktpnsiaaismkn
  

  
  
• Chain 'G':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2xrsG (G:)
  apqtitelcseyrntqiytindkilsytesmagkremviitfksgetfqvevpgsqhids
  qkkaiermkdtlrityltetkidklcvwnnktpnsiaaismkn
  

  
  
• Chain 'H':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2xrsH (H:)
  apqtitelcseyrntqiytindkilsytesmagkremviitfksgetfqvevpgsqhids
  qkkaiermkdtlrityltetkidklcvwnnktpnsiaaismkn
  

  
  
• Chain 'L':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2xrsL (L:)
  apqtitelcseyrntqiytindkilsytesmagkremviitfksgetfqvevpgsqhids
  qkkaiermkdtlrityltetkidklcvwnnktpnsiaaismkn
  

  
  
• Chain 'M':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2xrsM (M:)
  apqtitelcseyrntqiytindkilsytesmagkremviitfksgetfqvevpgsqhids
  qkkaiermkdtlrityltetkidklcvwnnktpnsiaaismkn
  

  
  
• Chain 'N':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2xrsN (N:)
  apqtitelcseyrntqiytindkilsytesmagkremviitfksgetfqvevpgsqhids
  qkkaiermkdtlrityltetkidklcvwnnktpnsiaaismkn
  

  
  
• Chain 'O':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2xrsO (O:)
  apqtitelcseyrntqiytindkilsytesmagkremviitfksgetfqvevpgsqhids
  qkkaiermkdtlrityltetkidklcvwnnktpnsiaaismkn
  

  
  
• Chain 'P':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2xrsP (P:)
  apqtitelcseyrntqiytindkilsytesmagkremviitfksgetfqvevpgsqhids
  qkkaiermkdtlrityltetkidklcvwnnktpnsiaaismkn