PDB entry 2xra

View 2xra on RCSB PDB site
Description: crystal structure of the hk20 fab in complex with a gp41 mimetic 5- helix
Deposited on 2010-09-13, released 2010-12-15
The last revision was dated 2018-02-07, with a file datestamp of 2018-02-02.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transmembrane protein gp41
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04578 (177-216)
      • insertion (41-42)
      • insertion (84-85)
      • insertion (87-88)
      • insertion (133)
      • insertion (172-173)
  • Chain 'H':
    Compound: hk20, human monoclonal antibody heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2XRA (0-222)
  • Chain 'L':
    Compound: hk20, human monoclonal antibody light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2XRA (0-214)
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2xraA (A:)
mqllsgivqqqnnllraieaqqhllqltvwgikqlqarilaggsgghttwmewdreinny
tslihslieesqnqqekneqellegssggqllsgivqqqnnllraieaqqhllqltvwgi
kqlqarilaggsgghttwmewdreinnytslihslieesqnqqekneqellegssggqll
sgivqqqnnllraieaqqhllqltvwgikqlqarilalegghhhhhhg

    Sequence, based on observed residues (ATOM records):
    >2xraA (A:)
qllsgivqqqnnllraieaqqhllqltvwgikqlqarilaggttwmewdreinnytslih
slieesqnqqekneqellegsggqllsgivqqqnnllraieaqqhllqltvwgikqlqar
ilghttwmewdreinnytslihslieesqnqqekneqellegsqllsgivqqqnnllrai
eaqqhllqltvwgikqlqarila

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records:
    >2xraH (H:)
qlvesgaevkkpgssvkvscktsggtfnrlamswvrqapgqglewmggimpifditnyaq
kfqgrvtiitdeststaymelrsltsedsavyycarasysssspyafdiwgqgtmvtvss
astkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records:
    >2xraL (L:)
diqmtqspsslspsvgdrvtitcqasqdirnhlnwyqqkpgkapklliydasnlatgvps
rfsgsgsgtdftftisslqpedlatyycqhyddlpritfgqgtrleikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglsspvtksfnrggc