PDB entry 2xqk

View 2xqk on RCSB PDB site
Description: x-ray structure of human butyrylcholinesterase inhibited by pure enantiomer vx-(s)
Class: hydrolase
Keywords: hydrolase, nerve agent, bioscavenger
Deposited on 2010-09-02, released 2011-03-23
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-05-18, with a file datestamp of 2011-05-13.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.15959
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cholinesterase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06276 (0-526)
      • engineered mutation (14)
      • engineered mutation (452)
      • engineered mutation (478)
      • engineered mutation (483)
    Domains in SCOPe 2.01: d2xqka_
  • Heterogens: GLY, VX, SO4, CA, NA, CL, K, FUC, NAG, UNX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2xqkA (A:)
diiiatkngkvrgmqltvfggtvtaflgipyaqpplgrlrfkkpqsltkwsdiwnatkya
nsccqnidqsfpgfhgsemwnpntdlsedclylnvwipapkpknatvliwiygggfqtgt
sslhvydgkflarvervivvsmnyrvgalgflalpgnpeapgnmglfdqqlalqwvqkni
aafggnpksvtlfgesagaasvslhllspgshslftrailqsgsfnapwavtslyearnr
tlnlakltgcsreneteiikclrnkdpqeillneafvvpygtplsvnfgptvdgdfltdm
pdillelgqfkktqilvgvnkdegtaflvygapgfskdnnsiitrkefqeglkiffpgvs
efgkesilfhytdwvddqrpenyrealgdvvgdynficpaleftkkfsewgnnaffyyfe
hrssklpwpewmgvmhgyeiefvfglplerrdqytkaeeilsrsivkrwanfakygnpqe
tqnqstswpvfksteqkyltlntestrimtklraqqcrfwtsffpkv