PDB entry 2xp2
View 2xp2 on RCSB PDB site
Description: Structure of the Human Anaplastic Lymphoma Kinase in Complex with Crizotinib (PF-02341066)
Class: transferase
Keywords: crizotinib, transferase
Deposited on
2010-08-24, released
2010-09-15
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-05-15, with a file datestamp of
2019-05-10.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: tyrosine-protein kinase receptor
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2xp2a_ - Heterogens: VGH, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2xp2A (A:)
mahhhhhhnpnycfagktssisdlkevprknitlirglghgafgevyegqvsgmpndpsp
lqvavktlpevcseqdeldflmealiiskfnhqnivrcigvslqslprfillelmaggdl
ksflretrprpsqpsslamldllhvardiacgcqyleenhfihrdiaarnclltcpgpgr
vakigdfgmardiyrasyyrkggcamlpvkwmppeafmegiftsktdtwsfgvllweifs
lgympypsksnqevlefvtsggrmdppkncpgpvyrimtqcwqhqpedrpnfaiilerie
yctqdpdvintalpieygplveeeekv
Sequence, based on observed residues (ATOM records): (download)
>2xp2A (A:)
npnycfagktssisdlkevprknitlirglgafgevyegqvsplqvavktlpevcseqde
ldflmealiiskfnhqnivrcigvslqslprfillelmaggdlksflretrprpsqslam
ldllhvardiacgcqyleenhfihrdiaarnclltcpgpgrvakigdfgmardiyramlp
vkwmppeafmegiftsktdtwsfgvllweifslgympypsksnqevlefvtsggrmdppk
ncpgpvyrimtqcwqhqpedrpnfaiilerieyctqdpdvintalpiey