PDB entry 2xnt

View 2xnt on RCSB PDB site
Description: acetylcholine binding protein (achbp) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors
Deposited on 2010-08-06, released 2011-08-24
The last revision was dated 2019-04-24, with a file datestamp of 2019-04-19.
Experiment type: XRAY
Resolution: 3.21 Å
R-factor: N/A
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8
      • conflict (59)
      • conflict (154)
  • Chain 'B':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8
      • conflict (59)
      • conflict (154)
  • Chain 'C':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8
      • conflict (59)
      • conflict (154)
  • Chain 'D':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8
      • conflict (59)
      • conflict (154)
  • Chain 'E':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8
      • conflict (59)
      • conflict (154)
  • Chain 'F':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8
      • conflict (59)
      • conflict (154)
  • Chain 'G':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8
      • conflict (59)
      • conflict (154)
  • Chain 'H':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8
      • conflict (59)
      • conflict (154)
  • Chain 'I':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8
      • conflict (59)
      • conflict (154)
  • Chain 'J':
    Compound: Soluble acetylcholine receptor
    Species: Aplysia californica [TaxId:6500]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8WSF8
      • conflict (59)
      • conflict (154)
  • Heterogens: VU2, BR

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2xntA (A:)
mlvsvylallvacvgqahsqanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkv
dsstnevdlvyyeqqrwklnslmwdpneygnitdfrtsaadiwtpditaysstrpvqvls
pqiavvthdgsvmfipaqrlsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqv
dlssyyasskyeilsatqtrqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records):
    >2xntA (A:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrer

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2xntB (B:)
mlvsvylallvacvgqahsqanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkv
dsstnevdlvyyeqqrwklnslmwdpneygnitdfrtsaadiwtpditaysstrpvqvls
pqiavvthdgsvmfipaqrlsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqv
dlssyyasskyeilsatqtrqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records):
    >2xntB (B:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrer

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2xntC (C:)
mlvsvylallvacvgqahsqanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkv
dsstnevdlvyyeqqrwklnslmwdpneygnitdfrtsaadiwtpditaysstrpvqvls
pqiavvthdgsvmfipaqrlsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqv
dlssyyasskyeilsatqtrqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records):
    >2xntC (C:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrer

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2xntD (D:)
mlvsvylallvacvgqahsqanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkv
dsstnevdlvyyeqqrwklnslmwdpneygnitdfrtsaadiwtpditaysstrpvqvls
pqiavvthdgsvmfipaqrlsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqv
dlssyyasskyeilsatqtrqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records):
    >2xntD (D:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrer

  • Chain 'E':
    Sequence, based on SEQRES records:
    >2xntE (E:)
mlvsvylallvacvgqahsqanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkv
dsstnevdlvyyeqqrwklnslmwdpneygnitdfrtsaadiwtpditaysstrpvqvls
pqiavvthdgsvmfipaqrlsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqv
dlssyyasskyeilsatqtrqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records):
    >2xntE (E:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrer

  • Chain 'F':
    Sequence, based on SEQRES records:
    >2xntF (F:)
mlvsvylallvacvgqahsqanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkv
dsstnevdlvyyeqqrwklnslmwdpneygnitdfrtsaadiwtpditaysstrpvqvls
pqiavvthdgsvmfipaqrlsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqv
dlssyyasskyeilsatqtrqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records):
    >2xntF (F:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrer

  • Chain 'G':
    Sequence, based on SEQRES records:
    >2xntG (G:)
mlvsvylallvacvgqahsqanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkv
dsstnevdlvyyeqqrwklnslmwdpneygnitdfrtsaadiwtpditaysstrpvqvls
pqiavvthdgsvmfipaqrlsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqv
dlssyyasskyeilsatqtrqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records):
    >2xntG (G:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrer

  • Chain 'H':
    Sequence, based on SEQRES records:
    >2xntH (H:)
mlvsvylallvacvgqahsqanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkv
dsstnevdlvyyeqqrwklnslmwdpneygnitdfrtsaadiwtpditaysstrpvqvls
pqiavvthdgsvmfipaqrlsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqv
dlssyyasskyeilsatqtrqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records):
    >2xntH (H:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrer

  • Chain 'I':
    Sequence, based on SEQRES records:
    >2xntI (I:)
mlvsvylallvacvgqahsqanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkv
dsstnevdlvyyeqqrwklnslmwdpneygnitdfrtsaadiwtpditaysstrpvqvls
pqiavvthdgsvmfipaqrlsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqv
dlssyyasskyeilsatqtrqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records):
    >2xntI (I:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrer

  • Chain 'J':
    Sequence, based on SEQRES records:
    >2xntJ (J:)
mlvsvylallvacvgqahsqanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkv
dsstnevdlvyyeqqrwklnslmwdpneygnitdfrtsaadiwtpditaysstrpvqvls
pqiavvthdgsvmfipaqrlsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqv
dlssyyasskyeilsatqtrqvqhysccpepyidvnlvvkfrerragngffrnlfd

    Sequence, based on observed residues (ATOM records):
    >2xntJ (J:)
qanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkvdsstnevdlvyyeqqrwkl
nslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqr
lsfmcdptgvdseegvtcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqt
rqvqhysccpepyidvnlvvkfrer