PDB entry 2xns

View 2xns on RCSB PDB site
Description: crystal structure of human g alpha i1 bound to a designed helical peptide derived from the goloco motif of rgs14
Deposited on 2010-08-05, released 2011-06-08
The last revision was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 3.41 Å
R-factor: N/A
AEROSPACI score: 0.09 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Guanine nucleotide-binding protein G(i) subunit alpha-1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Guanine nucleotide-binding protein G(i) subunit alpha-1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: regulator of g-protein signaling 14
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O43566 (0-20)
      • expression tag (21-38)
  • Chain 'D':
    Compound: regulator of g-protein signaling 14
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O43566 (0-20)
      • expression tag (21-38)
  • Heterogens: GDP, SRT, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2xnsA (A:)
snaarevkllllgagesgkstivkqmkiiheagyseeeckqykavvysntiqsiiaiira
mgrlkidfgdsaraddarqlfvlagaaeegfmtaelagvikrlwkdsgvqacfnrsreyq
lndsaayylndldriaqpnyiptqqdvlrtrvkttgivethftfkdlhfkmfdvggqrse
rkkwihcfegvtaiifcvalsdydlvlaedeemnrmhesmklfdsicnnkwftdtsiilf
lnkkdlfeekikksplticypeyagsntyeeaaayiqcqfedlnkrkdtkeiythftcat
dtknvqfvfdavtdviiknnlkdcglf

    Sequence, based on observed residues (ATOM records):
    >2xnsA (A:)
revkllllgagesgkstivkqmkiiheagyseeeckqykavvysntiqsiiaiiramgrl
kidfgdsaraddarqlfvlagaaeegfmtaelagvikrlwkdsgvqacfnrsreyqlnds
aayylndldriaqpnyiptqqdvlrtrvkttgivethftfkdlhfkmfdvggqrserkkw
ihcfegvtaiifcvalsdydlvlaedeemnrmhesmklfdsicnnkwftdtsiilflnkk
dlfeekikksplticypeyagsntyeeaaayiqcqfedlnkrkdtkeiythftcatdtkn
vqfvfdavtdviiknn

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2xnsB (B:)
snaarevkllllgagesgkstivkqmkiiheagyseeeckqykavvysntiqsiiaiira
mgrlkidfgdsaraddarqlfvlagaaeegfmtaelagvikrlwkdsgvqacfnrsreyq
lndsaayylndldriaqpnyiptqqdvlrtrvkttgivethftfkdlhfkmfdvggqrse
rkkwihcfegvtaiifcvalsdydlvlaedeemnrmhesmklfdsicnnkwftdtsiilf
lnkkdlfeekikksplticypeyagsntyeeaaayiqcqfedlnkrkdtkeiythftcat
dtknvqfvfdavtdviiknnlkdcglf

    Sequence, based on observed residues (ATOM records):
    >2xnsB (B:)
revkllllgagesgkstivkqmkiiheagyseeeckqykavvysntiqsiiaiiramgrl
kidfgdsaraddarqlfvlagaaeegfmtaelagvikrlwkdsgvqacfnrsreyqlnds
aayylndldriaqpnyiptqqdvlrtrvkttgivethftfkdlhfkmfdvggqrserkkw
ihcfegvtaiifcvalsdydlvlaedeemnrmhesmklfdsicnnkwftdtsiilflnkk
dlfeekikksplticypeyagsntyeeaaayiqcqfedlnkrkdtkeiythftcatdtkn
vqfvfdavtdviiknn

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2xnsC (C:)
dieglvellnrvqssgahdqrgllsneevfralrdfdrwf

    Sequence, based on observed residues (ATOM records):
    >2xnsC (C:)
dieglvellnrvqssgahdqrgllsneevfralrdfdrw

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2xnsD (D:)
dieglvellnrvqssgahdqrgllsneevfralrdfdrwf

    Sequence, based on observed residues (ATOM records):
    >2xnsD (D:)
dieglvellnrvqssgahdqrgllsneevfralrdfdrw