PDB entry 2xng
View 2xng on RCSB PDB site
Description: structure of aurora-a bound to a selective imidazopyrazine inhibitor
Class: transferase
Keywords: ser-thr protein kinase complex, proto-oncogene, kinase, mitosis, cell cycle, microtubule, transferase, cytoskeleton, cell division
Deposited on
2010-08-02, released
2010-09-22
The last revision prior to the SCOPe 2.05 freeze date was dated
2010-09-29, with a file datestamp of
2010-09-24.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.2238
AEROSPACI score: 0.28
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: serine/threonine-protein kinase 6
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d2xnga_ - Heterogens: A0H, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2xngA (A:)
meskkrqwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrr
eveiqshlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitel
analsychskrvihrdikpenlllgsagelkiadfgwsvhapssrrttlcgtldylppem
iegrmhdekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardli
srllkhnpsqrpmlrevlehpwitansskpsncqnkesaskqs
Sequence, based on observed residues (ATOM records): (download)
>2xngA (A:)
qwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiqs
hlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanalsy
chskrvihrdikpenlllgsagelkiadfgwsvhatldylppemiegrmhdekvdlwslg
vlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhnpsqrpmlre
vlehpwitansskp