PDB entry 2xm9

View 2xm9 on RCSB PDB site
Description: structure of a small molecule inhibitor with the kinase domain of chk2
Class: transferase
Keywords: transferase, cancer
Deposited on 2010-07-26, released 2011-01-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-02-16, with a file datestamp of 2011-02-11.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.189
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine/threonine-protein kinase chk2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2xm9a_
  • Heterogens: LWH, NO3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2xm9A (A:)
gplgshmsvypkalrdeyimsktlgsgacgevklaferktckkvaikiiskrkfaigsar
eadpalnveteieilkklnhpciikiknffdaedyyivlelmeggelfdkvvgnkrlkea
tcklyfyqmllavqylhengiihrdlkpenvllssqeedclikitdfghskilgetslmr
tlcgtptylapevlvsvgtagynravdcwslgvilficlsgyppfsehrtqvslkdqits
gkynfipevwaevsekaldlvkkllvvdpkarftteealrhpwlqdedmkrkfqdllsee
nestalpqvlaqpstsrkrpregeaegae

    Sequence, based on observed residues (ATOM records): (download) 
    >2xm9A (A:)
vypkalrdeyimsktlgsgevklaferktckkvaikiiskpalnveteieilkklnhpci
ikiknffdaedyyivlelmeggelfdkvvgnkrlkeatcklyfyqmllavqylhengiih
rdlkpenvllssqeedclikitdfghskilgetslmrtlcgtptylapevlvsvgtagyn
ravdcwslgvilficlsgyppfsehrtqvslkdqitsgkynfipevwaevsekaldlvkk
llvvdpkarftteealrhpwlqdedmkrkfqdllseenestalpqvl