PDB entry 2xlr

View 2xlr on RCSB PDB site
Description: joint-functions of protein residues and nadp(h) in oxygen-activation by flavin-containing monooxygenase: asn78asp mutant
Deposited on 2010-07-21, released 2010-09-15
The last revision was dated 2019-02-27, with a file datestamp of 2019-02-22.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Flavin-containing monooxygenase
    Species: METHYLOPHAGA AMINISULFIDIVORANS [TaxId:230105]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q83XK4 (5-End)
      • engineered mutation (77)
      • conflict (157-158)
  • Chain 'B':
    Compound: Flavin-containing monooxygenase
    Species: METHYLOPHAGA AMINISULFIDIVORANS [TaxId:230105]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q83XK4 (5-End)
      • engineered mutation (77)
      • conflict (157-158)
  • Chain 'C':
    Compound: Flavin-containing monooxygenase
    Species: METHYLOPHAGA AMINISULFIDIVORANS [TaxId:230105]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q83XK4 (5-End)
      • expression tag (4)
      • engineered mutation (77)
      • conflict (157-158)
  • Chain 'D':
    Compound: Flavin-containing monooxygenase
    Species: METHYLOPHAGA AMINISULFIDIVORANS [TaxId:230105]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q83XK4 (5-End)
      • expression tag (4)
      • engineered mutation (77)
      • conflict (157-158)
  • Heterogens: FAD, NAP, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2xlrA (A:)
    gamgsmatriailgagpsgmaqlrafqsaqekgaeipelvcfekqadwggqwnytwrtgl
    dengepvhssmyrylwsdgpkeclefadytfdehfgkpiasypprevlwdyikgrvekag
    vrkyirfntavrhvefnedsqtftvtvqdhttdtiysaafdyvvcctghfstpyvpefeg
    fekfggrilhahdfrdalefkdktvllvgssysaedigsqcykygakkliscyrtapmgy
    kwpenwderpnlvrvdtenayfadgssekvdaiilctgyihhfpflnddlrlvtnnrlwp
    lnlykgvvwednpkffyigmqdqwysfnmfdaqawyardvimgrlplpskeemkadsmaw
    rekeltlvtaeemytyqgdyiqnlidmtdypsfdipatnktflewkhhkkenimtfrdhs
    yrslmtgtmapkhhtpwidalddsleaylsdkseipvakea
    

    Sequence, based on observed residues (ATOM records):
    >2xlrA (A:)
    matriailgagpsgmaqlrafqsaqekgaeipelvcfekqadwggqwnytwrtgldenge
    pvhssmyrylwsdgpkeclefadytfdehfgkpiasypprevlwdyikgrvekagvrkyi
    rfntavrhvefnedsqtftvtvqdhttdtiysaafdyvvcctghfstpyvpefegfekfg
    grilhahdfrdalefkdktvllvgssysaedigsqcykygakkliscyrtapmgykwpen
    wderpnlvrvdtenayfadgssekvdaiilctgyihhfpflnddlrlvtnnrlwplnlyk
    gvvwednpkffyigmqdqwysfnmfdaqawyardvimgrlplpskeemkadsmawrekel
    tlvtaeemytyqgdyiqnlidmtdypsfdipatnktflewkhhkkenimtfrdhsyrslm
    tgtmapkhhtpwidalddsleaylsd
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2xlrB (B:)
    gamgsmatriailgagpsgmaqlrafqsaqekgaeipelvcfekqadwggqwnytwrtgl
    dengepvhssmyrylwsdgpkeclefadytfdehfgkpiasypprevlwdyikgrvekag
    vrkyirfntavrhvefnedsqtftvtvqdhttdtiysaafdyvvcctghfstpyvpefeg
    fekfggrilhahdfrdalefkdktvllvgssysaedigsqcykygakkliscyrtapmgy
    kwpenwderpnlvrvdtenayfadgssekvdaiilctgyihhfpflnddlrlvtnnrlwp
    lnlykgvvwednpkffyigmqdqwysfnmfdaqawyardvimgrlplpskeemkadsmaw
    rekeltlvtaeemytyqgdyiqnlidmtdypsfdipatnktflewkhhkkenimtfrdhs
    yrslmtgtmapkhhtpwidalddsleaylsdkseipvakea
    

    Sequence, based on observed residues (ATOM records):
    >2xlrB (B:)
    matriailgagpsgmaqlrafqsaqekgaeipelvcfekqadwggqwnytwrtgldenge
    pvhssmyrylwsdgpkeclefadytfdehfgkpiasypprevlwdyikgrvekagvrkyi
    rfntavrhvefnedsqtftvtvqdhttdtiysaafdyvvcctghfstpyvpefegfekfg
    grilhahdfrdalefkdktvllvgssysaedigsqcykygakkliscyrtapmgykwpen
    wderpnlvrvdtenayfadgssekvdaiilctgyihhfpflnddlrlvtnnrlwplnlyk
    gvvwednpkffyigmqdqwysfnmfdaqawyardvimgrlplpskeemkadsmawrekel
    tlvtaeemytyqgdyiqnlidmtdypsfdipatnktflewkhhkkenimtfrdhsyrslm
    tgtmapkhhtpwidalddsleaylsdk
    

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2xlrC (C:)
    gamgsmatriailgagpsgmaqlrafqsaqekgaeipelvcfekqadwggqwnytwrtgl
    dengepvhssmyrylwsdgpkeclefadytfdehfgkpiasypprevlwdyikgrvekag
    vrkyirfntavrhvefnedsqtftvtvqdhttdtiysaafdyvvcctghfstpyvpefeg
    fekfggrilhahdfrdalefkdktvllvgssysaedigsqcykygakkliscyrtapmgy
    kwpenwderpnlvrvdtenayfadgssekvdaiilctgyihhfpflnddlrlvtnnrlwp
    lnlykgvvwednpkffyigmqdqwysfnmfdaqawyardvimgrlplpskeemkadsmaw
    rekeltlvtaeemytyqgdyiqnlidmtdypsfdipatnktflewkhhkkenimtfrdhs
    yrslmtgtmapkhhtpwidalddsleaylsdkseipvakea
    

    Sequence, based on observed residues (ATOM records):
    >2xlrC (C:)
    smatriailgagpsgmaqlrafqsaqekgaeipelvcfekqadwggqwnytwrtgldeng
    epvhssmyrylwsdgpkeclefadytfdehfgkpiasypprevlwdyikgrvekagvrky
    irfntavrhvefnedsqtftvtvqdhttdtiysaafdyvvcctghfstpyvpefegfekf
    ggrilhahdfrdalefkdktvllvgssysaedigsqcykygakkliscyrtapmgykwpe
    nwderpnlvrvdtenayfadgssekvdaiilctgyihhfpflnddlrlvtnnrlwplnly
    kgvvwednpkffyigmqdqwysfnmfdaqawyardvimgrlplpskeemkadsmawreke
    ltlvtaeemytyqgdyiqnlidmtdypsfdipatnktflewkhhkkenimtfrdhsyrsl
    mtgtmapkhhtpwidalddsleaylsdkseip
    

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2xlrD (D:)
    gamgsmatriailgagpsgmaqlrafqsaqekgaeipelvcfekqadwggqwnytwrtgl
    dengepvhssmyrylwsdgpkeclefadytfdehfgkpiasypprevlwdyikgrvekag
    vrkyirfntavrhvefnedsqtftvtvqdhttdtiysaafdyvvcctghfstpyvpefeg
    fekfggrilhahdfrdalefkdktvllvgssysaedigsqcykygakkliscyrtapmgy
    kwpenwderpnlvrvdtenayfadgssekvdaiilctgyihhfpflnddlrlvtnnrlwp
    lnlykgvvwednpkffyigmqdqwysfnmfdaqawyardvimgrlplpskeemkadsmaw
    rekeltlvtaeemytyqgdyiqnlidmtdypsfdipatnktflewkhhkkenimtfrdhs
    yrslmtgtmapkhhtpwidalddsleaylsdkseipvakea
    

    Sequence, based on observed residues (ATOM records):
    >2xlrD (D:)
    smatriailgagpsgmaqlrafqsaqekgaeipelvcfekqadwggqwnytwrtgldeng
    epvhssmyrylwsdgpkeclefadytfdehfgkpiasypprevlwdyikgrvekagvrky
    irfntavrhvefnedsqtftvtvqdhttdtiysaafdyvvcctghfstpyvpefegfekf
    ggrilhahdfrdalefkdktvllvgssysaedigsqcykygakkliscyrtapmgykwpe
    nwderpnlvrvdtenayfadgssekvdaiilctgyihhfpflnddlrlvtnnrlwplnly
    kgvvwednpkffyigmqdqwysfnmfdaqawyardvimgrlplpskeemkadsmawreke
    ltlvtaeemytyqgdyiqnlidmtdypsfdipatnktflewkhhkkenimtfrdhsyrsl
    mtgtmapkhhtpwidalddsleaylsd