PDB entry 2xk9

View 2xk9 on RCSB PDB site
Description: structural analysis of checkpoint kinase 2 (chk2) in complex with inhibitor pv1533
Class: transferase
Keywords: structure-based drug design, transferase
Deposited on 2010-07-07, released 2011-07-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-11-16, with a file datestamp of 2011-11-11.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.19982
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: checkpoint kinase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2xk9a_
  • Heterogens: XK9, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2xk9A (A:)
svypkalrdeyimsktlgsgacgevklaferktckkvaikiiskrkfaigsareadpaln
veteieilkklnhpciikiknffdaedyyivlelmeggelfdkvvgnkrlkeatcklyfy
qmllavqylhengiihrdlkpenvllssqeedclikitdfghskilgetslmrtlcgtpt
ylapevlvsvgtagynravdcwslgvilficlsgyppfsehrtqvslkdqitsgkynfip
evwaevsekaldlvkkllvvdpkarftteealrhpwlqdedmkrkfqdllseenestalp
qvlaqpstsrkrpregeaegae

    Sequence, based on observed residues (ATOM records): (download) 
    >2xk9A (A:)
vypkalrdeyimsktlgsgagevklaferktckkvaikiisknveteieilkklnhpcii
kiknffdaedyyivlelmeggelfdkvvgnkrlkeatcklyfyqmllavqylhengiihr
dlkpenvllssqeedclikitdfghskilgetslmrtlcgtptylapevlvsvgtagynr
avdcwslgvilficlsgyppfsehrtqvslkdqitsgkynfipevwaevsekaldlvkkl
lvvdpkarftteealrhpwlqdedmkrkfqdllseenestalpq