PDB entry 2xjg

View 2xjg on RCSB PDB site
Description: Structure of HSP90 with small molecule inhibitor bound
Class: chaperone
Keywords: chaperone, ATP binding domain, stress response
Deposited on 2010-07-06, released 2010-08-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-04-01, with a file datestamp of 2015-03-27.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Heat shock protein HSP 90-alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07900
      • conflict (75)
    Domains in SCOPe 2.08: d2xjga_
  • Heterogens: XJG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2xjgA (A:)
    mgsshhhhhhssglvprgshmdqpmeeeevetfafqaeiaqlmsliintfysnkeiflre
    lisnssdaldkiryetltdpskldsgkelhinlipnkqdrtltivdtgigmtkadlinnl
    gtiaksgtkafmealqagadismigqfgvgfysaylvaekvtvitkhnddeqyawessag
    gsftvrtdtgepmgrgtkvilhlkedqteyleerrikeivkkhsqfigypitlfvekerd
    kevsddeae
    

    Sequence, based on observed residues (ATOM records): (download)
    >2xjgA (A:)
    pmeeeevetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryetltdpskl
    dsgkelhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadism
    igqfgvgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhl
    kedqteyleerrikeivkkhsqfigypitlfve