PDB entry 2xje

View 2xje on RCSB PDB site
Description: crystal structure of the d52n variant of cytosolic 5'-nucleotidase ii in complex with uridine 5'-monophosphate and adenosine triphosphate
Deposited on 2010-07-04, released 2011-03-16
The last revision was dated 2011-04-27, with a file datestamp of 2011-04-22.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.21749
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cytosolic purine 5'-nucleotidase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49902
      • engineered mutation (70)
  • Heterogens: U5P, ATP, GOL, MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2xjeA (A:)
mgsshhhhhhssglvprgsmstswsdrlqnaadmpanmdkhalkkyrreayhrvfvnrsl
amekikcfgfnmdytlavykspeyeslgfeltverlvsigypqellsfaydstfptrglv
fdtlygnllkvdaygnllvcahgfnfirgpetreqypnkfiqrddterfyilntlfnlpe
tyllaclvdfftncprytscetgfkdgdlfmsyrsmfqdvrdavdwvhykgslkektven
lekyvvkdgklplllsrmkevgkvflatnsdykytdkimtylfdfphgpkpgsshrpwqs
yfdlilvdarkplffgegtvlrqvdtktgklkigtytgplqhgivysggssdticdllga
kgkdilyigdhifgdilkskkrqgwrtflvipelaqelhvwtdksslfeelqsldiflae
lykhldsssnerpdissiqrrikkvthdmdmcygmmgslfrsgsrqtlfasqvmryadly
aasfinllyypfsylfraahvlmphestvehthvdinemesplatrnrtsvdfkdtdykr
hqltrsiseikppnl

    Sequence, based on observed residues (ATOM records):
    >2xjeA (A:)
tswsdrlqnaadmpanmdkhalkkyrreayhrvfvnrslamekikcfgfnmdytlavyks
peyeslgfeltverlvsigypqellsfaydstfptrglvfdtlygnllkvdaygnllvca
hgfnfirgpetreqypnkfiqrddterfyilntlfnlpetyllaclvdfftncprytsce
tgfkdgdlfmsyrsmfqdvrdavdwvhykgslkektvenlekyvvkdgklplllsrmkev
gkvflatnsdykytdkimtylfdfphgpkpgsshrpwqsyfdlilvdarkplffgegtvl
rqvdtktgklkigtytgplqhgivysggssdticdllgakgkdilyigdhifgdilkskk
rqgwrtflvipelaqelhvwtdksslfeelqsldifqrrikkvthdmdmcygmmgslfrs
gsrqtlfasqvmryadlyaasfinllyypfsylfraahvlmphes