PDB entry 2xiq

View 2xiq on RCSB PDB site
Description: crystal structure of human methylmalonyl-coa mutase in complex with adenosylcobalamin and malonyl-coa
Deposited on 2010-06-30, released 2010-09-29
The last revision was dated 2019-11-20, with a file datestamp of 2019-11-15.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: methylmalonyl-coa mutase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22033
      • conflict (488)
  • Chain 'B':
    Compound: methylmalonyl-coa mutase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22033
      • conflict (488)
  • Heterogens: B12, 5AD, MLC, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2xiqA (A:)
msphylrqvkessgsrliqqrllhqqqplhpewaalakkqlkgknpedliwhtpegisik
plyskrdtmdlpeelpgvkpftrgpyptmytfrpwtirqyagfstveesnkfykdnikag
qqglsvafdlathrgydsdnprvrgdvgmagvaidtvedtkilfdgiplekmsvsmtmng
avipvlanfivtgeeqgvpkekltgtiqndilkefmvrntyifppepsmkiiadifeyta
khmpkfnsisisgyhmqeagadailelaytladgleysrtglqagltidefaprlsffwg
igmnfymeiakmragrrlwahliekmfqpknskslllrahcqtsgwslteqdpynnivrt
aieamaavfggtqslhtnsfdealglptvksariarntqiiiqeesgipkvadpwggsym
mecltndvydaalklineieemggmakavaegipklrieecaarrqaridsgsevivgvn
kyqlekedtvevlaidntsvrnrqieklkkikssrdqalaerclaaltecaasgdgnila
lavdasrarctvgeitdalkkvfgehkandrmvsgayrqefgeskeitsaikrvhkfmer
egrrprllvakmgqdghdrgakviatgfadlgfdvdigplfqtprevaqqavdadvhavg
vstlaaghktlvpelikelnslgrpdilvmcggvippqdyeflfevgvsnvfgpgtripk
aavqvlddiekclekkqqsvaenlyfqshhhhhhdykddddk

    Sequence, based on observed residues (ATOM records):
    >2xiqA (A:)
qqplhpewaalakkqlkgknpedliwhtpegisikplyskrdtmdlpeelpgvkpftrgp
yptmytfrpwtirqyagfstveesnkfykdnikagqqglsvafdlathrgydsdnprvrg
dvgmagvaidtvedtkilfdgiplekmsvsmtmngavipvlanfivtgeeqgvpkekltg
tiqndilkefmvrntyifppepsmkiiadifeytakhmpkfnsisisgyhmqeagadail
elaytladgleysrtglqagltidefaprlsffwgigmnfymeiakmragrrlwahliek
mfqpknskslllrahcqtsgwslteqdpynnivrtaieamaavfggtqslhtnsfdealg
lptvksariarntqiiiqeesgipkvadpwggsymmecltndvydaalklineieemggm
akavaegipklrieecaarrqaridsgsevivgvnkyqlekedtvevlaidntsvrnrqi
eklkkikssrdqalaerclaaltecaasgdgnilalavdasrarctvgeitdalkkvfge
hkandrmvsgayrqefgeskeitsaikrvhkfmeregrrprllvakmgqdghdrgakvia
tgfadlgfdvdigplfqtprevaqqavdadvhavgvstlaaghktlvpelikelnslgrp
dilvmcggvippqdyeflfevgvsnvfgpgtripkaavqvlddiekclekkqqs

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2xiqB (B:)
msphylrqvkessgsrliqqrllhqqqplhpewaalakkqlkgknpedliwhtpegisik
plyskrdtmdlpeelpgvkpftrgpyptmytfrpwtirqyagfstveesnkfykdnikag
qqglsvafdlathrgydsdnprvrgdvgmagvaidtvedtkilfdgiplekmsvsmtmng
avipvlanfivtgeeqgvpkekltgtiqndilkefmvrntyifppepsmkiiadifeyta
khmpkfnsisisgyhmqeagadailelaytladgleysrtglqagltidefaprlsffwg
igmnfymeiakmragrrlwahliekmfqpknskslllrahcqtsgwslteqdpynnivrt
aieamaavfggtqslhtnsfdealglptvksariarntqiiiqeesgipkvadpwggsym
mecltndvydaalklineieemggmakavaegipklrieecaarrqaridsgsevivgvn
kyqlekedtvevlaidntsvrnrqieklkkikssrdqalaerclaaltecaasgdgnila
lavdasrarctvgeitdalkkvfgehkandrmvsgayrqefgeskeitsaikrvhkfmer
egrrprllvakmgqdghdrgakviatgfadlgfdvdigplfqtprevaqqavdadvhavg
vstlaaghktlvpelikelnslgrpdilvmcggvippqdyeflfevgvsnvfgpgtripk
aavqvlddiekclekkqqsvaenlyfqshhhhhhdykddddk

    Sequence, based on observed residues (ATOM records):
    >2xiqB (B:)
qqplhpewaalakkqlkgknpedliwhtpegisikplyskrdtmdlpeelpgvkpftrgp
yptmytfrpwtirqyagfstveesnkfykdnikagqqglsvafdlathrgydsdnprvrg
dvgmagvaidtvedtkilfdgiplekmsvsmtmngavipvlanfivtgeeqgvpkekltg
tiqndilkefmvrntyifppepsmkiiadifeytakhmpkfnsisisgyhmqeagadail
elaytladgleysrtglqagltidefaprlsffwgigmnfymeiakmragrrlwahliek
mfqpknskslllrahcqtsgwslteqdpynnivrtaieamaavfggtqslhtnsfdealg
lptvksariarntqiiiqeesgipkvadpwggsymmecltndvydaalklineieemggm
akavaegipklrieecaarrqaridsgsevivgvnkyqlekedtvevlaidntsvrnrqi
eklkkikssrdqalaerclaaltecaasgdgnilalavdasrarctvgeitdalkkvfge
hkandrmvsgayrqefgeskeitsaikrvhkfmeregrrprllvakmgqdghdrgakvia
tgfadlgfdvdigplfqtprevaqqavdadvhavgvstlaaghktlvpelikelnslgrp
dilvmcggvippqdyeflfevgvsnvfgpgtripkaavqvlddiekclekkqq