PDB entry 2xip

View 2xip on RCSB PDB site
Description: crystal structure of the DNA binding domain of human tp73 refined at 1.8 a resolution
Class: cell cycle
Keywords: phosphoprotein, tumor suppressor, transcription, metal-binding, nucleus, cell cycle, transcription regulation
Deposited on 2010-06-30, released 2010-07-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-11-17, with a file datestamp of 2010-11-12.
Experiment type: XRAY
Resolution: 1.82 Å
R-factor: 0.18812
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tumour protein p73
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15350 (1-200)
      • expression tag (201-207)
    Domains in SCOPe 2.08: d2xipa1, d2xipa2
  • Heterogens: ZN, NI, TAM, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2xipA (A:)
    mapvipsntdypgphhfevtfqqsstaksatwtyspllkklycqiaktcpiqikvstppp
    pgtairampvykkaehvtdvvkrcpnhelgrdfnegqsapashlirvegnnlsqyvddpv
    tgrqsvvvpyeppqvgtefttilynfmcnsscvggmnrrpiliiitlemrdgqvlgrrsf
    egricacpgrdrkadedhyreaenlyfq
    

    Sequence, based on observed residues (ATOM records): (download)
    >2xipA (A:)
    apvipsntdypgphhfevtfqqsstaksatwtyspllkklycqiaktcpiqikvstpppp
    gtairampvykkaehvtdvvkrcpnhelgrdfnegqsapashlirvegnnlsqyvddpvt
    grqsvvvpyeppqvgtefttilynfmcnsscvgrrpiliiitlemrdgqvlgrrsfegri
    cacpgrdrkadedhyreaenlyfq