PDB entry 2xht
View 2xht on RCSB PDB site
Description: structure of hsp90 with small molecule inhibitor bound
Class: chaperone
Keywords: chaperone, inhibitor,
Deposited on
2010-06-21, released
2010-09-01
The last revision prior to the SCOPe 2.08 freeze date was dated
2010-09-01, with a file datestamp of
2010-08-27.
Experiment type: XRAY
Resolution: 2.27 Å
R-factor: 0.2286
AEROSPACI score: 0.32
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Heat shock protein HSP 90-alpha
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2xhta_ - Heterogens: C0Y, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2xhtA (A:)
mgsshhhhhhssglvprgshmdqpmeeeevetfafqaeiaqlmsliintfysnkeiflre
lisnssdaldkiryesltdpskldsgkelhinlipnkqdrtltivdtgigmtkadlinnl
gtiaksgtkafmealqagadismigqfgvgfysaylvaekvtvitkhnddeqyawessag
gsftvrtdtgepmgrgtkvilhlkedqteyleerrikeivkkhsqfigypitlfvekerd
kevsddeae
Sequence, based on observed residues (ATOM records): (download)
>2xhtA (A:)
meeeevetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskld
sgkelhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadismi
gqfgvgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhlk
edqteyleerrikeivkkhsqfigypitlfvek