PDB entry 2xge

View 2xge on RCSB PDB site
Description: crystal structure of a designed heterodimeric variant t-a(a) b of the tetracycline repressor
Deposited on 2010-06-03, released 2010-09-22
The last revision was dated 2010-10-20, with a file datestamp of 2010-10-15.
Experiment type: XRAY
Resolution: 2.14 Å
R-factor: 0.2097
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tetracycline repressor protein class b from transposon tn10, tetracycline repressor protein class d
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04483 (Start-49)
      • engineered mutation (135)
      • engineered mutation (192)
      • engineered mutation (196)
    • Uniprot P0ACT4 (50-207)
  • Chain 'B':
    Compound: tetracycline repressor protein class b from transposon tn10, tetracycline repressor protein class d
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04483 (Start-52)
      • engineered mutation (142)
      • engineered mutation (194)
    • Uniprot P0ACT4 (53-210)
  • Heterogens: EDO, NA, CL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2xgeA (A:)
msrldkskvinsalellnevgieglttrklaqklgveqptlywhvknkralldalaveil
arhhdyslpaageswqsflrnnamsfrrallryrdgakvhlgtrpdekqydtvetqlrfm
tengfslrdglyaiswvshftlgavleqqehtaaltdrpaapdenlppllrealqimdsd
dgeqaflhglesairgievqltallqiv

    Sequence, based on observed residues (ATOM records):
    >2xgeA (A:)
srldkskvinsalellnevgieglttrklaqklgveqptlywhvknkralldalaveila
rhhdyslpaageswqsflrnnamsfrrallryrdgakvhlgtrpdekqydtvetqlrfmt
engfslrdglyaiswvshftlgavleqqehlppllrealqimdsddgeqaflhglesair
gievqltallqiv

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2xgeB (B:)
gshmsrldkskvinsalellnevgieglttrklaqklgveqptlywhvknkralldalav
eilarhhdyslpaageswqsflrnnamsfrrallryrdgakvhlgtrpdekqydtvetql
rfmtengfslrdglyaisavshatlgavleqqehtaaltdrpaapdenlppllrealqim
dsddgeqaflhglewlirgfevqltallqiv

    Sequence, based on observed residues (ATOM records):
    >2xgeB (B:)
srldkskvinsalellnevgieglttrklaqklgveqptlywhvknkralldalaveila
rhhdyslpaageswqsflrnnamsfrrallryrdgakvhlgtrpdekqydtvetqlrfmt
engfslrdglyaisavshatlgavleqqehlppllrealqimdsddgeqaflhglewlir
gfevqltallqiv