PDB entry 2xfs

View 2xfs on RCSB PDB site
Description: structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway
Deposited on 2010-05-26, released 2011-06-29
The last revision was dated 2018-02-21, with a file datestamp of 2018-02-16.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: orf12
    Species: Streptomyces clavuligerus [TaxId:1901]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q83Z62
      • engineered mutation (172)
  • Chain 'B':
    Compound: orf12
    Species: Streptomyces clavuligerus [TaxId:1901]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q83Z62
      • engineered mutation (172)
  • Heterogens: J01, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2xfsA (A:)
mmkkadsvptpaeaalaaqtalaaddspmgdaarwamglltssglprpedvaarfiptfa
aagnfaetvrewrskgpftvrayhpvahkgwvvlsapagvryilsltldssgliriltlk
petvipdmvtwndveetlhtpgvqhsvyavrltpdghevlhasaperpmptgaayklylm
ralvaeiekgtvgwdeiltltpelrslptgdmqdlpdgtrvtvretahkmialsdntgad
lvadrlgrevverslaaaghhdpslmrpfltshevfelgwgdperraewvrqdeagrrel
lekmagvmtvrgsdlgatvhqlgidwhmdafdvvrvlegllqdsgrdtsgtveeiltayp
gllideerwrrvyfkagsspgvmmfcwllqdhagisyvlvlrqsadeqrligdglflrgi
gakiieaeakllssgerrgagtaaagddrasageaarr

    Sequence, based on observed residues (ATOM records):
    >2xfsA (A:)
vptpaeaalaaqtalaaddspmgdaarwamglltssrpedvaarfiptfnfaetvrewrs
kgpftvrayhpvahkgwvvlsapagvryilsltldssgliriltlkpetvipdmvtwndv
eetlhtpgvqhsvyavrltpdghevlhasaperpmptgaayklylmralvaeiekgtvgw
deiltltpelrslptgdmqdlpdgtrvtvretahkmialsdntgadlvadrlgrevvers
laaaghhdpslmrpfltshevfelgwgdperraewvrqdeagrrellekmagvmtvrgsd
lgatvhqlgidwhmdafdvvrvlegllqdsgrdtsgtveeiltaypgllideerwrrvyf
kagsspgvmmfcwllqdhagisyvlvlrqsadeqrligdglflrgigakiieaeakllss

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2xfsB (B:)
mmkkadsvptpaeaalaaqtalaaddspmgdaarwamglltssglprpedvaarfiptfa
aagnfaetvrewrskgpftvrayhpvahkgwvvlsapagvryilsltldssgliriltlk
petvipdmvtwndveetlhtpgvqhsvyavrltpdghevlhasaperpmptgaayklylm
ralvaeiekgtvgwdeiltltpelrslptgdmqdlpdgtrvtvretahkmialsdntgad
lvadrlgrevverslaaaghhdpslmrpfltshevfelgwgdperraewvrqdeagrrel
lekmagvmtvrgsdlgatvhqlgidwhmdafdvvrvlegllqdsgrdtsgtveeiltayp
gllideerwrrvyfkagsspgvmmfcwllqdhagisyvlvlrqsadeqrligdglflrgi
gakiieaeakllssgerrgagtaaagddrasageaarr

    Sequence, based on observed residues (ATOM records):
    >2xfsB (B:)
vptpaeaalaaqtalaaddspmgdaarwamglltssglprpedvaarfiptfnfaetvre
wrskgpftvrayhpvahkgwvvlsapagvryilsltldssgliriltlkpetvipdmvtw
ndveetlhtpgvqhsvyavrltpdghevlhasaperpmptgaayklylmralvaeiekgt
vgwdeiltltpelrslptgdmqdlpdgtrvtvretahkmialsdntgadlvadrlgrevv
erslaaaghhdpslmrpfltshevfelgwgdperraewvrqdeagrrellekmagvmtvr
gsdlgatvhqlgidwhmdafdvvrvlegllqdsgrdtsgtveeiltaypgllideerwrr
vyfkagsspgvmmfcwllqdhagisyvlvlrqsadeqrligdglflrgigakiieaeakl
lssg