PDB entry 2xfl

View 2xfl on RCSB PDB site
Description: induced-fit and allosteric effects upon polyene binding revealed by crystal structures of the dynemicin thioesterase
Class: hydrolase
Keywords: hydrolase, polyketide biosynthesis, enediyne, hot-dog fold
Deposited on 2010-05-26, released 2010-10-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-11-24, with a file datestamp of 2010-11-19.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.1988
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dyne7
    Species: MICROMONOSPORA CHERSINA [TaxId:47854]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2xfla_
  • Chain 'B':
    Compound: dyne7
    Species: MICROMONOSPORA CHERSINA [TaxId:47854]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2xflb_
  • Chain 'C':
    Compound: dyne7
    Species: MICROMONOSPORA CHERSINA [TaxId:47854]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2xflc_
  • Chain 'D':
    Compound: dyne7
    Species: MICROMONOSPORA CHERSINA [TaxId:47854]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2xfld_
  • Chain 'E':
    Compound: dyne7
    Species: MICROMONOSPORA CHERSINA [TaxId:47854]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2xfle_
  • Chain 'F':
    Compound: dyne7
    Species: MICROMONOSPORA CHERSINA [TaxId:47854]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2xflf_
  • Chain 'G':
    Compound: dyne7
    Species: MICROMONOSPORA CHERSINA [TaxId:47854]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2xflg_
  • Chain 'H':
    Compound: dyne7
    Species: MICROMONOSPORA CHERSINA [TaxId:47854]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2xflh_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2xflA (A:)
dsyvhrhvvtfdetnlvgnvyfahylhwqghcrehfladhapgvmaaladglalvtvdch
adfyaegsafdevevrmmldrldghriamsfdyvrvapgpptllaqgrqtvacmrraghg
lepvevpaelrralsryavvar

    Sequence, based on observed residues (ATOM records): (download) 
    >2xflA (A:)
dsyvhrhvvtfdetnlvgnvyfahylhwqghcrehfladhapgvmaaladglalvtvdch
adfyaegsafdevevrmmldrldghriamsfdyvrvapgpptllaqgrqtvacmrraghg
lepvevpaelrralsry

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2xflB (B:)
dsyvhrhvvtfdetnlvgnvyfahylhwqghcrehfladhapgvmaaladglalvtvdch
adfyaegsafdevevrmmldrldghriamsfdyvrvapgpptllaqgrqtvacmrraghg
lepvevpaelrralsryavvar

    Sequence, based on observed residues (ATOM records): (download) 
    >2xflB (B:)
dsyvhrhvvtfdetnlvgnvyfahylhwqghcrehfladhapgvmaaladglalvtvdch
adfyaegsafdevevrmmldrldghriamsfdyvrvapgpptllaqgrqtvacmrraghg
lepvevpaelrralsryavva

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2xflC (C:)
dsyvhrhvvtfdetnlvgnvyfahylhwqghcrehfladhapgvmaaladglalvtvdch
adfyaegsafdevevrmmldrldghriamsfdyvrvapgpptllaqgrqtvacmrraghg
lepvevpaelrralsryavvar

    Sequence, based on observed residues (ATOM records): (download) 
    >2xflC (C:)
dsyvhrhvvtfdetnlvgnvyfahylhwqghcrehfladhapgvmaaladglalvtvdch
adfyaegsafdevevrmmldrldghriamsfdyvrvapgpptllaqgrqtvacmrraghg
lepvevpaelrralsr

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2xflD (D:)
dsyvhrhvvtfdetnlvgnvyfahylhwqghcrehfladhapgvmaaladglalvtvdch
adfyaegsafdevevrmmldrldghriamsfdyvrvapgpptllaqgrqtvacmrraghg
lepvevpaelrralsryavvar

    Sequence, based on observed residues (ATOM records): (download) 
    >2xflD (D:)
dsyvhrhvvtfdetnlvgnvyfahylhwqghcrehfladhapgvmaaladglalvtvdch
adfyaegsafdevevrmmldrldghriamsfdyvrvapgpptllaqgrqtvacmrraghg
lepvevpaelrralsryavva

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2xflE (E:)
dsyvhrhvvtfdetnlvgnvyfahylhwqghcrehfladhapgvmaaladglalvtvdch
adfyaegsafdevevrmmldrldghriamsfdyvrvapgpptllaqgrqtvacmrraghg
lepvevpaelrralsryavvar

    Sequence, based on observed residues (ATOM records): (download) 
    >2xflE (E:)
dsyvhrhvvtfdetnlvgnvyfahylhwqghcrehfladhapgvmaaladglalvtvdch
adfyaegsafdevevrmmldrldghriamsfdyvrvapgpptllaqgrqtvacmrraghg
lepvevpaelrralsr

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2xflF (F:)
dsyvhrhvvtfdetnlvgnvyfahylhwqghcrehfladhapgvmaaladglalvtvdch
adfyaegsafdevevrmmldrldghriamsfdyvrvapgpptllaqgrqtvacmrraghg
lepvevpaelrralsryavvar

    Sequence, based on observed residues (ATOM records): (download) 
    >2xflF (F:)
dsyvhrhvvtfdetnlvgnvyfahylhwqghcrehfladhapgvmaaladglalvtvdch
adfyaegsafdevevrmmldrldghriamsfdyvrvapgpptllaqgrqtvacmrraghg
lepvevpaelrralsrya

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2xflG (G:)
dsyvhrhvvtfdetnlvgnvyfahylhwqghcrehfladhapgvmaaladglalvtvdch
adfyaegsafdevevrmmldrldghriamsfdyvrvapgpptllaqgrqtvacmrraghg
lepvevpaelrralsryavvar

    Sequence, based on observed residues (ATOM records): (download) 
    >2xflG (G:)
dsyvhrhvvtfdetnlvgnvyfahylhwqghcrehfladhapgvmaaladglalvtvdch
adfyaegsafdevevrmmldrldghriamsfdyvrvapgpptllaqgrqtvacmrraghg
lepvevpaelrralsryavva

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2xflH (H:)
dsyvhrhvvtfdetnlvgnvyfahylhwqghcrehfladhapgvmaaladglalvtvdch
adfyaegsafdevevrmmldrldghriamsfdyvrvapgpptllaqgrqtvacmrraghg
lepvevpaelrralsryavvar

    Sequence, based on observed residues (ATOM records): (download) 
    >2xflH (H:)
dsyvhrhvvtfdetnlvgnvyfahylhwqghcrehfladhapgvmaaladglalvtvdch
adfyaegsafdevevrmmldrldghriamsfdyvrvapgpptllaqgrqtvacmrraghg
lepvevpaelrralsryavva