PDB entry 2xf0
View 2xf0 on RCSB PDB site
Description: crystal structure of checkpoint kinase 1 (chk1) in complex with inhibitors
Class: transferase
Keywords: transferase, DNA repair, cell cycle
Deposited on
2010-05-19, released
2010-06-30
The last revision prior to the SCOPe 2.05 freeze date was dated
2010-07-21, with a file datestamp of
2010-07-16.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.2045
AEROSPACI score: 0.33
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Serine/threonine-protein kinase Chk1
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d2xf0a_ - Heterogens: 4UB, EDO, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2xf0A (A:)
mavpfvedwdlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicink
mlnhenvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvy
lhgigithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellk
rrefhaepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsapla
llhkilvenpsaritipdikkdrwynkplkkgakrprvtsggvsespsg
Sequence, based on observed residues (ATOM records): (download)
>2xf0A (A:)
pfvedwdlvqtlgevqlavnrvteeavavkivdnikkeicinkmlnhenvvkfyghrrei
qylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgigithrdikpenllld
erdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefhaepvdvwscgivlt
amlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhkilvenpsaritipdi
kkdrwynkplk