PDB entry 2xe7

View 2xe7 on RCSB PDB site
Description: the complete reaction cycle of human phosphoglycerate kinase: the open ternary complex with 3pg and ADP
Class: transferase
Keywords: transition state analogue, hereditary hemolytic anemia, phosphoprotein, glycolysis, transferase, phosphoryl transfer, nucleotide-binding, domain motions
Deposited on 2010-05-11, released 2011-01-19
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-10-26, with a file datestamp of 2011-10-21.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.22757
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphoglycerate kinase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2xe7a_
  • Heterogens: 3PG, ADP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2xe7A (A:)
    mslsnkltldkldvkgkrvvmrvdfnvpmknnqitnnqrikaavpsikfcldngaksvvl
    mshlgrpdgvpmpdkyslepvavelksllgkdvlflkdcvgpevekacanpaagsville
    nlrfhveeegkgkdasgnkvkaepakieafraslsklgdvyvndafgtahrahssmvgvn
    lpqkaggflmkkelnyfakalesperpflailggakvadkiqlinnmldkvnemiigggm
    aftflkvlnnmeigtslfdeegakivkdlmskaekngvkitlpvdfvtadkfdenaktgq
    atvasgipagwmgldcgpesskkyaeavtrakqivwngpvgvfeweafargtkalmdevv
    katsrgcitiigggdtatccakwntedkvshvstgggaslellegkvlpgvdalsni
    

    Sequence, based on observed residues (ATOM records): (download)
    >2xe7A (A:)
    nkltldkldvkgkrvvmrvdfnvpmknnqitnnqrikaavpsikfcldngaksvvlmshl
    grpdgvpmpdkyslepvavelksllgkdvlflkdcvgpevekacanpaagsvillenlrf
    hveeegkgkdasgnkvkaepakieafraslsklgdvyvndafgtahrahssmvgvnlpqk
    aggflmkkelnyfakalesperpflailggakvadkiqlinnmldkvnemiigggmaftf
    lkvlnnmeigtslfdeegakivkdlmskaekngvkitlpvdfvtadkfdenaktgqatva
    sgipagwmgldcgpesskkyaeavtrakqivwngpvgvfeweafargtkalmdevvkats
    rgcitiigggdtatccakwntedkvshvstgggaslellegkvlpgvdalsni