PDB entry 2xdx
View 2xdx on RCSB PDB site
Description: Structure of HSP90 with small molecule inhibitor bound
Class: chaperone
Keywords: chaperone, inhibitor, stress response
Deposited on
2010-05-10, released
2010-09-01
The last revision prior to the SCOPe 2.08 freeze date was dated
2016-12-14, with a file datestamp of
2016-12-09.
Experiment type: XRAY
Resolution: 2.42 Å
R-factor: N/A
AEROSPACI score: 0.21
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Heat shock protein HSP 90-alpha
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2xdxa_ - Heterogens: WOE, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2xdxA (A:)
mgsshhhhhhssglvprgshmdqpmeeeevetfafqaeiaqlmsliintfysnkeiflre
lisnssdaldkiryesltdpskldsgkelhinlipnkqdrtltivdtgigmtkadlinnl
gtiaksgtkafmealqagadismigqfgvgfysaylvaekvtvitkhnddeqyawessag
gsftvrtdtgepmgrgtkvilhlkedqteyleerrikeivkkhsqfigypitlfvekerd
kevsddeae
Sequence, based on observed residues (ATOM records): (download)
>2xdxA (A:)
pmeeeevetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskl
dsgkelhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadism
igqfgvgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhl
kedqteyleerrikeivkkhsqfigypitlfvek