PDB entry 2xcw

View 2xcw on RCSB PDB site
Description: crystal structure of the d52n variant of cytosolic 5'-nucleotidase ii in complex with inosine monophosphate and atp
Deposited on 2010-04-26, released 2011-03-16
The last revision was dated 2011-04-27, with a file datestamp of 2011-04-22.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.16814
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cytosolic purine 5'-nucleotidase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49902
      • engineered mutation (69)
  • Heterogens: ATP, IMP, GOL, MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2xcwA (A:)
gsshhhhhhssglvprgsmstswsdrlqnaadmpanmdkhalkkyrreayhrvfvnrsla
mekikcfgfnmdytlavykspeyeslgfeltverlvsigypqellsfaydstfptrglvf
dtlygnllkvdaygnllvcahgfnfirgpetreqypnkfiqrddterfyilntlfnlpet
yllaclvdfftncprytscetgfkdgdlfmsyrsmfqdvrdavdwvhykgslkektvenl
ekyvvkdgklplllsrmkevgkvflatnsdykytdkimtylfdfphgpkpgsshrpwqsy
fdlilvdarkplffgegtvlrqvdtktgklkigtytgplqhgivysggssdticdllgak
gkdilyigdhifgdilkskkrqgwrtflvipelaqelhvwtdksslfeelqsldiflael
ykhldsssnerpdissiqrrikkvthdmdmcygmmgslfrsgsrqtlfasqvmryadlya
asfinllyypfsylfraahvlmphestvehthvdinemesplatrnrtsvdfkdtdykrh
qltrsiseikppnl

    Sequence, based on observed residues (ATOM records):
    >2xcwA (A:)
tswsdrlqnaadmpanmdkhalkkyrreayhrvfvnrslamekikcfgfnmdytlavyks
peyeslgfeltverlvsigypqellsfaydstfptrglvfdtlygnllkvdaygnllvca
hgfnfirgpetreqypnkfiqrddterfyilntlfnlpetyllaclvdfftncprytsce
tgfkdgdlfmsyrsmfqdvrdavdwvhykgslkektvenlekyvvkdgklplllsrmkev
gkvflatnsdykytdkimtylfdfphgpkpgsshrpwqsyfdlilvdarkplffgegtvl
rqvdtktgklkigtytgplqhgivysggssdticdllgakgkdilyigdhifgdilkskk
rqgwrtflvipelaqelhvwtdksslfeelqsldiflassiqrrikkvthdmdmcygmmg
slfrsgsrqtlfasqvmryadlyaasfinllyypfsylfraahvlmphes