PDB entry 2xcv

View 2xcv on RCSB PDB site
Description: crystal structure of the d52n variant of cytosolic 5'- nucleotidase ii in complex with inosine monophosphate and 2,3-bisphosphoglycerate
Deposited on 2010-04-26, released 2011-03-16
The last revision was dated 2016-07-20, with a file datestamp of 2016-07-15.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cytosolic purine 5'-nucleotidase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49902
      • engineered mutation (69)
  • Heterogens: DG2, GOL, IMP, MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2xcvA (A:)
gsshhhhhhssglvprgsmstswsdrlqnaadmpanmdkhalkkyrreayhrvfvnrsla
mekikcfgfnmdytlavykspeyeslgfeltverlvsigypqellsfaydstfptrglvf
dtlygnllkvdaygnllvcahgfnfirgpetreqypnkfiqrddterfyilntlfnlpet
yllaclvdfftncprytscetgfkdgdlfmsyrsmfqdvrdavdwvhykgslkektvenl
ekyvvkdgklplllsrmkevgkvflatnsdykytdkimtylfdfphgpkpgsshrpwqsy
fdlilvdarkplffgegtvlrqvdtktgklkigtytgplqhgivysggssdticdllgak
gkdilyigdhifgdilkskkrqgwrtflvipelaqelhvwtdksslfeelqsldiflael
ykhldsssnerpdissiqrrikkvthdmdmcygmmgslfrsgsrqtlfasqvmryadlya
asfinllyypfsylfraahvlmphestvehthvdinemesplatrnrtsvdfkdtdykrh
qltrsiseikppnl

    Sequence, based on observed residues (ATOM records):
    >2xcvA (A:)
tswsdrlqnaadmpanmdkhalkkyrreayhrvfvnrslamekikcfgfnmdytlavyks
peyeslgfeltverlvsigypqellsfaydstfptrglvfdtlygnllkvdaygnllvca
hgfnfirgpetreqypnkfiqrddterfyilntlfnlpetyllaclvdfftncprytsce
tgfkdgdlfmsyrsmfqdvrdavdwvhykgslkektvenlekyvvkdgklplllsrmkev
gkvflatnsdykytdkimtylfdfphgpkpgsshrpwqsyfdlilvdarkplffgegtvl
rqvdtktgklkigtytgplqhgivysggssdticdllgakgkdilyigdhifgdilkskk
rqgwrtflvipelaqelhvwtdksslfeelqsldrrikkvthdmdmcygmmgslfrsgsr
qtlfasqvmryadlyaasfinllyypfsylfraahvlmphes