PDB entry 2xc4

View 2xc4 on RCSB PDB site
Description: Factor Xa in complex with a pyrrolidine-3,4-dicarboxylic acid inhibitor
Class: blood clotting
Keywords: blood clotting, coagulation factor, egf-like domain, gamma-carboxyglutamic acid, hydrolase, hydroxylation, zymogen
Deposited on 2010-04-16, released 2010-08-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-06-28, with a file datestamp of 2017-06-23.
Experiment type: XRAY
Resolution: 1.67 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: activated factor xa heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2xc4a_
  • Chain 'L':
    Compound: factor x light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2xc4l_
  • Heterogens: CA, NA, IVK, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2xc4A (A:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktrglpka
k

    Sequence, based on observed residues (ATOM records): (download) 
    >2xc4A (A:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >2xc4L (L:)
rklcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtlerr

    Sequence, based on observed residues (ATOM records): (download) 
    >2xc4L (L:)
klcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtlerr