PDB entry 2xc0

View 2xc0 on RCSB PDB site
Description: factor xa in complex with a pyrrolidine-3,4-dicarboxylic acid inhibitor
Class: blood clotting
Keywords: blood clotting, coagulation factor, hydrolase, hydroxylation, serine protease, zymogen
Deposited on 2010-04-15, released 2010-08-04
The last revision prior to the SCOPe 2.01 freeze date was dated 2010-08-25, with a file datestamp of 2010-08-20.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.18684
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: activated factor xa heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2xc0a_
  • Chain 'L':
    Compound: factor x light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2xc0l_
  • Heterogens: 8NC, CA, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2xc0A (A:)
    ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
    qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
    tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
    cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktrglpka
    k
    

    Sequence, based on observed residues (ATOM records): (download)
    >2xc0A (A:)
    ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
    qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
    tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
    cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktr
    

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >2xc0L (L:)
    rklcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtlerr
    

    Sequence, based on observed residues (ATOM records): (download)
    >2xc0L (L:)
    csldngdcdqfcvvcscargytladngkaciptgpypcgkqtler