PDB entry 2xbv

View 2xbv on RCSB PDB site
Description: factor xa in complex with a pyrrolidine-3,4-dicarboxylic acid inhibitor
Class: blood clotting
Keywords: blood clotting, coagulation factor, hydrolase, hydroxylation, serine protease, zymogen
Deposited on 2010-04-15, released 2010-08-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-08-25, with a file datestamp of 2010-08-20.
Experiment type: XRAY
Resolution: 1.66 Å
R-factor: 0.1936
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: activated factor xa heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00742 (0-End)
      • engineered mutation (137)
    Domains in SCOPe 2.08: d2xbva_
  • Chain 'L':
    Compound: factor x light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2xbvl_
  • Heterogens: XBV, CA, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2xbvA (A:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgeqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktrglpka
k

    Sequence, based on observed residues (ATOM records): (download) 
    >2xbvA (A:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgeqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktr

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >2xbvL (L:)
rklcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtlerr

    Sequence, based on observed residues (ATOM records): (download) 
    >2xbvL (L:)
csdngdcdqfcvvcscargytladngkaciptgpypcgkqtler