PDB entry 2xbn

View 2xbn on RCSB PDB site
Description: inhibition of the plp-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation
Deposited on 2010-04-13, released 2010-05-19
The last revision was dated 2010-08-25, with a file datestamp of 2010-08-20.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: 0.15704
AEROSPACI score: 0.71 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine palmitoyltransferase
    Species: SPHINGOMONAS PAUCIMOBILIS [TaxId:13689]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: PMP, MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2xbnA (A:)
    teaaaqphalpadapdiaperdllskfdgliaerqklldsgvtdpfaivmeqvkspteav
    irgkdtillgtynymgmtfdpdviaagkealekfgsgtngsrmlngtfhdhmeveqalrd
    fygttgaivfstgymanlgiistlagkgeyvildadshasiydgcqqgnaeivrfrhnsv
    edldkrlgrlpkepaklvvlegvysmlgdiaplkemvavakkhgamvlvdeahsmgffgp
    ngrgvyeaqglegqidfvvgtfsksvgtvggfvvsnhpkfeavrlacrpyiftaslppsv
    vatattsirklmtahekrerlwsnaralhgglkamgfrlgtetcdsaivavmledqeqaa
    mmwqalldgglyvnmarppatpagtfllrcsicaehtpaqiqtvlgmfqaagravgvigl
    ehhhhhh
    

    Sequence, based on observed residues (ATOM records):
    >2xbnA (A:)
    rdllskfdgliaerqklldsgvtdpfaivmeqvkspteavirgkdtillgtynymgmtfd
    pdviaagkealekfgsgtngsrmlngtfhdhmeveqalrdfygttgaivfstgymanlgi
    istlagkgeyvildadshasiydgcqqgnaeivrfrhnsvedldkrlgrlpkepaklvvl
    egvysmlgdiaplkemvavakkhgamvlvdeahsmgffgpngrgvyeaqglegqidfvvg
    tfsksvgtvggfvvsnhpkfeavrlacrpyiftaslppsvvatattsirklmtahekrer
    lwsnaralhgglkamgfrlgtetcdsaivavmledqeqaammwqalldgglyvnmarppa
    tpagtfllrcsicaehtpaqiqtvlgmfqaagravgvi