PDB entry 2xbj

View 2xbj on RCSB PDB site
Description: crystal structure of chk2 in complex with an inhibitor
Class: transferase
Keywords: transferase, DNA repair, parp
Deposited on 2010-04-12, released 2011-01-12
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-02-16, with a file datestamp of 2011-02-11.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.1962
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine/threonine-protein kinase chk2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2xbja_
  • Heterogens: XBJ, MG, NO3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2xbjA (A:)
gplgshmsvypkalrdeyimsktlgsgacgevklaferktckkvaikiiskrkfaigsar
eadpalnveteieilkklnhpciikiknffdaedyyivlelmeggelfdkvvgnkrlkea
tcklyfyqmllavqylhengiihrdlkpenvllssqeedclikitdfghskilgetslmr
tlcgtptylapevlvsvgtagynravdcwslgvilficlsgyppfsehrtqvslkdqits
gkynfipevwaevsekaldlvkkllvvdpkarftteealrhpwlqdedmkrkfqdllsee
nestalpqvlaqpstsrkrpregeaegae

    Sequence, based on observed residues (ATOM records): (download) 
    >2xbjA (A:)
vypkalrdeyimsktlgsgagevklaferktckkvaikiiskalnveteieilkklnhpc
iikiknffdaedyyivlelmeggelfdkvvgnkrlkeatcklyfyqmllavqylhengii
hrdlkpenvllssqeedclikitdfghskiltslmrtlcgtptylapevlvsvgtagynr
avdcwslgvilficlsgyppfsehrtqvslkdqitsgkynfipevwaevsekaldlvkkl
lvvdpkarftteealrhpwlqdedmkrkfqdllseenestalpqvl