PDB entry 2xb8

View 2xb8 on RCSB PDB site
Description: Structure of Mycobacterium tuberculosis type II dehydroquinase in complex with inhibitor compound (2R)-2-(4-methoxybenzyl)-3- dehydroquinic acid
Class: lyase
Keywords: lyase, amino acid biosynthesis
Deposited on 2010-04-08, released 2010-09-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-02-07, with a file datestamp of 2018-02-02.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-dehydroquinate dehydratase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2xb8a_
  • Heterogens: XNW, SO4, TRS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2xb8A (A:)
selivnvingpnlgrlgrrepavyggtthdelvaliereaaelglkavvrqsdseaqlld
wihqaadaaepvilnagglthtsvalrdacaelsaplievhisnvhareefrrhsylspi
atgvivglgiqgyllalrylaehvgt

    Sequence, based on observed residues (ATOM records): (download) 
    >2xb8A (A:)
livnvingpnlgrlgrrepavyggtthdelvaliereaaelglkavvrqsdseaqlldwi
hqaadaaepvilnagglthtsvalrdacaelsaplievhisnvhareefrrhsylspiat
gvivglgiqgyllalrylaeh