PDB entry 2xb7

View 2xb7 on RCSB PDB site
Description: structure of human anaplastic lymphoma kinase in complex with nvp-tae684
Class: transferase
Keywords: ATP-binding, receptor, transferase
Deposited on 2010-04-08, released 2010-07-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-08-25, with a file datestamp of 2010-08-20.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.195
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ALK tyrosine kinase receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2xb7a_
  • Heterogens: GUI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2xb7A (A:)
gpnycfagktssisdlkevprknitlirglghgafgevyegqvsgmpndpsplqvavktl
pevcseqdeldflmealiiskfnhqnivrcigvslqslprfillelmaggdlksflretr
prpsqpsslamldllhvardiacgcqyleenhfihrdiaarnclltcpgpgrvakigdfg
mardiyrasyyrkggcamlpvkwmppeafmegiftsktdtwsfgvllweifslgympyps
ksnqevlefvtsggrmdppkncpgpvyrimtqcwqhqpedrpnfaiilerieyctqdpdv
intalpieygplvee

    Sequence, based on observed residues (ATOM records): (download) 
    >2xb7A (A:)
nycfagktssisdlkevprknitlirglghgafgevyegqvsplqvavktlpevcseqde
ldflmealiiskfnhqnivrcigvslqslprfillelmaggdlksflretrprpsqpssl
amldllhvardiacgcqyleenhfihrdiaarnclltcpgpgrvakigdfgmaamlpvkw
mppeafmegiftsktdtwsfgvllweifslgympypsksnqevlefvtsggrmdppkncp
gpvyrimtqcwqhqpedrpnfaiilerieyctqdpdvintalpiey