PDB entry 2xae

View 2xae on RCSB PDB site
Description: crystal structure of human kinesin eg5 in complex with (r)-2-amino-3-((s)-2-methyl-1,1-diphenylbutylthio)propanoic acid
Class: cell cycle
Keywords: cell cycle, mitosis, ksp
Deposited on 2010-03-31, released 2011-03-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-05-25, with a file datestamp of 2011-05-20.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.18512
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Kinesin-like protein KIF11
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2xaea_
  • Chain 'B':
    Compound: Kinesin-like protein KIF11
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2xaeb_
  • Chain 'C':
    Compound: Kinesin-like protein KIF11
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2xaec_
  • Heterogens: 2XA, MG, ADP, CL, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2xaeA (A:)
masqpnssakkkeekgkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladk
ssrktytfdmvfgastkqidvyrsvvcpildevimgynctifaygqtgtgktftmegers
pneeytweedplagiiprtlhqifekltdngtefsvkvslleiyneelfdllnpssdvse
rlqmfddprnkrgviikgleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfs
vtihmkettidgeelvkigklnlvdlagsenigrsgavdkrareagninqslltlgrvit
alvertphvpyreskltrilqdslggrtrtsiiatispaslnleetlstleyahraknil
nkpevnqk

    Sequence, based on observed residues (ATOM records): (download) 
    >2xaeA (A:)
kniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfdmvfgast
kqidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagii
prtlhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgvii
kgleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkeeelvkigkl
nlvdlagsenninqslltlgrvitalvertphvpyreskltrilqdslggrtrtsiiati
spaslnleetlstleyahraknilnkpe

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2xaeB (B:)
masqpnssakkkeekgkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladk
ssrktytfdmvfgastkqidvyrsvvcpildevimgynctifaygqtgtgktftmegers
pneeytweedplagiiprtlhqifekltdngtefsvkvslleiyneelfdllnpssdvse
rlqmfddprnkrgviikgleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfs
vtihmkettidgeelvkigklnlvdlagsenigrsgavdkrareagninqslltlgrvit
alvertphvpyreskltrilqdslggrtrtsiiatispaslnleetlstleyahraknil
nkpevnqk

    Sequence, based on observed residues (ATOM records): (download) 
    >2xaeB (B:)
kniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfdmvfgast
kqidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagii
prtlhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgvii
kgleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkeeelvkigkl
nlvdlagsenninqslltlgrvitalvertphvpyreskltrilqdslggrtrtsiiati
spaslnleetlstleyahraknilnkpe

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2xaeC (C:)
masqpnssakkkeekgkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladk
ssrktytfdmvfgastkqidvyrsvvcpildevimgynctifaygqtgtgktftmegers
pneeytweedplagiiprtlhqifekltdngtefsvkvslleiyneelfdllnpssdvse
rlqmfddprnkrgviikgleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfs
vtihmkettidgeelvkigklnlvdlagsenigrsgavdkrareagninqslltlgrvit
alvertphvpyreskltrilqdslggrtrtsiiatispaslnleetlstleyahraknil
nkpevnqk

    Sequence, based on observed residues (ATOM records): (download) 
    >2xaeC (C:)
niqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfdmvfgastk
qidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagiip
rtlhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgviik
gleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkettidgeelvk
igklnlvdlagsennqslltlgrvitalvertphvpyreskltrilqdslggrtrtsiia
tispaslnleetlstleyahraknilnkp