PDB entry 2xad

View 2xad on RCSB PDB site
Description: crystal structure of deacetylase-teicoplanin complex in biosynthesis pathway of teicoplanin
Deposited on 2010-03-31, released 2011-03-02
The last revision was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: n-acyl glm peudo-teicoplanin deacetylase
    Species: Actinoplanes teichomyceticus [TaxId:1867]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6ZZJ1 (Start-272)
      • engineered mutation (163)
  • Chain 'B':
    Compound: n-acyl glm peudo-teicoplanin deacetylase
    Species: Actinoplanes teichomyceticus [TaxId:1867]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6ZZJ1 (Start-272)
      • engineered mutation (163)
  • Chain 'C':
    Compound: n-acyl glm peudo-teicoplanin deacetylase
    Species: Actinoplanes teichomyceticus [TaxId:1867]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6ZZJ1 (Start-272)
      • engineered mutation (163)
  • Chain 'D':
    Compound: n-acyl glm peudo-teicoplanin deacetylase
    Species: Actinoplanes teichomyceticus [TaxId:1867]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6ZZJ1 (Start-272)
      • engineered mutation (163)
  • Chain 'E':
    Compound: teicoplanin
    Species: NONOMURAEA SP. ATCC 39727 [TaxId:93944]
    Database cross-references and differences (RAF-indexed):
    • PDB 2XAD (0-6)
  • Chain 'F':
    Compound: teicoplanin
    Species: NONOMURAEA SP. ATCC 39727 [TaxId:93944]
    Database cross-references and differences (RAF-indexed):
    • PDB 2XAD (0-6)
  • Chain 'G':
    Compound: teicoplanin
    Species: NONOMURAEA SP. ATCC 39727 [TaxId:93944]
    Database cross-references and differences (RAF-indexed):
    • PDB 2XAD (0-6)
  • Chain 'H':
    Compound: teicoplanin
    Species: NONOMURAEA SP. ATCC 39727 [TaxId:93944]
    Database cross-references and differences (RAF-indexed):
    • PDB 2XAD (0-6)
  • Heterogens: BMA, NAG, GCS, T55, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2xadA (A:)
mphdpgatrllaisphlddavlsfgaglaqaaqdganvlvytvfagaaqppyspaaqrmh
tiwglapdddavlyrrkediaaldhlrvahrhgrfldsiyrklpdgrwltahvegrqkla
vndhspdsdhdlvgevaddirsiidefdptlvvtcaaigehpdneatrdaalfatheknv
pvrlwedlpyavfksgavelpqgfrlgsadvssvkpemrsqkfqaveryssqmvllngse
nnlfdrldeharqnaphggygettwpvvrsdds

    Sequence, based on observed residues (ATOM records):
    >2xadA (A:)
atrllaisphlddavlsfgaglaqaaqdganvlvytvfagaaqppyspaaqrmhtiwgla
pdddavlyrrkediaaldhlrvahrhgrfldsiyrklpdgrwltahvegrqklavndhsp
dsdhdlvgevaddirsiidefdptlvvtcaaigehpdneatrdaalfatheknvpvrlwe
dlpyavfksgavelpqgfrlgsadvssvkpemrsqkfqaveryssqmvlfdrldeharqn
aphggygettwpvvrsdds

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2xadB (B:)
mphdpgatrllaisphlddavlsfgaglaqaaqdganvlvytvfagaaqppyspaaqrmh
tiwglapdddavlyrrkediaaldhlrvahrhgrfldsiyrklpdgrwltahvegrqkla
vndhspdsdhdlvgevaddirsiidefdptlvvtcaaigehpdneatrdaalfatheknv
pvrlwedlpyavfksgavelpqgfrlgsadvssvkpemrsqkfqaveryssqmvllngse
nnlfdrldeharqnaphggygettwpvvrsdds

    Sequence, based on observed residues (ATOM records):
    >2xadB (B:)
atrllaisphlddavlsfgaglaqaaqdganvlvytvfagaaqppyspaaqrmhtiwgla
pdddavlyrrkediaaldhlrvahrhgrfldsiyrklpdgrwltahvegrqklavndhsp
dsdhdlvgevaddirsiidefdptlvvtcaaigehpdneatrdaalfatheknvpvrlwe
dlpyavfksgavelpqgfrlgsadvssvkpemrsqkfqaveryssqmlfdrldeharqna
phggygettwpvvrsdds

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2xadC (C:)
mphdpgatrllaisphlddavlsfgaglaqaaqdganvlvytvfagaaqppyspaaqrmh
tiwglapdddavlyrrkediaaldhlrvahrhgrfldsiyrklpdgrwltahvegrqkla
vndhspdsdhdlvgevaddirsiidefdptlvvtcaaigehpdneatrdaalfatheknv
pvrlwedlpyavfksgavelpqgfrlgsadvssvkpemrsqkfqaveryssqmvllngse
nnlfdrldeharqnaphggygettwpvvrsdds

    Sequence, based on observed residues (ATOM records):
    >2xadC (C:)
trllaisphlddavlsfgaglaqaaqdganvlvytvfagaaqppyspaaqrmhtiwglap
dddavlyrrkediaaldhlrvahrhgrfldsiyrklpdgrwltahvegrqklavndhspd
sdhdlvgevaddirsiidefdptlvvtcaaigehpdneatrdaalfatheknvpvrlwed
lpyavfksgavelpqgfrlgsadvssvkpemrsqkfqaveryssqmvlfdrldeharqna
phggygettwpvvrsdds

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2xadD (D:)
mphdpgatrllaisphlddavlsfgaglaqaaqdganvlvytvfagaaqppyspaaqrmh
tiwglapdddavlyrrkediaaldhlrvahrhgrfldsiyrklpdgrwltahvegrqkla
vndhspdsdhdlvgevaddirsiidefdptlvvtcaaigehpdneatrdaalfatheknv
pvrlwedlpyavfksgavelpqgfrlgsadvssvkpemrsqkfqaveryssqmvllngse
nnlfdrldeharqnaphggygettwpvvrsdds

    Sequence, based on observed residues (ATOM records):
    >2xadD (D:)
trllaisphlddavlsfgaglaqaaqdganvlvytvfagaaqppyspaaqrmhtiwglap
dddavlyrrkediaaldhlrvahrhgrfldsiyrklpdgrwltahvegrqklavndhspd
sdhdlvgevaddirsiidefdptlvvtcaaigehpdneatrdaalfatheknvpvrlwed
lpyavfksgavelpqgfrlgsadvssvkpemrsqkfqaveryssqmlfdrldeharqnap
hggygettwpvvrsdds

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records:
    >2xadE (E:)
gxxggxx

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records:
    >2xadF (F:)
gxxggxx

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records:
    >2xadG (G:)
gxxggxx

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records:
    >2xadH (H:)
gxxggxx