PDB entry 2xac
View 2xac on RCSB PDB site
Description: structural insights into the binding of vegf-b by vegfr-1d2: recognition and specificity
Class: transferase/signaling protein
Keywords: transferase-signaling protein complex, angiogenesis, cysteine-knot protein, mitogen, transferase, signaling protein
Deposited on
2010-03-30, released
2010-05-19
The last revision prior to the SCOPe 2.04 freeze date was dated
2010-08-04, with a file datestamp of
2010-07-30.
Experiment type: XRAY
Resolution: 2.71 Å
R-factor: 0.286
AEROSPACI score: 0.17
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: vascular endothelial growth factor b
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d2xaca_ - Chain 'B':
Compound: vascular endothelial growth factor b
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d2xacb_ - Chain 'C':
Compound: vascular endothelial growth factor receptor 1
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d2xacc_ - Chain 'X':
Compound: vascular endothelial growth factor receptor 1
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d2xacx_ - Heterogens: GOL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>2xacA (A:)
hqrkvvswidvytratcqprevvvpltvelmgtvakqlvpscvtvqrcggccpddglecv
ptgqhqvrmqilmirypssqlgemsleehsqcecrpkkk
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2xacB (B:)
hqrkvvswidvytratcqprevvvpltvelmgtvakqlvpscvtvqrcggccpddglecv
ptgqhqvrmqilmirypssqlgemsleehsqcecrpkkk
Sequence, based on observed residues (ATOM records): (download)
>2xacB (B:)
qrkvvswidvytratcqprevvvpltvelmgtvakqlvpscvtvqrcggccpddglecvp
tgqhqvrmqilmirypssqlgemsleehsqcecrpkkk
- Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)
>2xacC (C:)
sdtgrpfvemyseipeiihmtegrelvipcrvtspnitvtlkkfpldtlipdgkriiwds
rkgfiisnatykeiglltceatvnghlyktnylthrqt
- Chain 'X':
Sequence, based on SEQRES records: (download)
>2xacX (X:)
sdtgrpfvemyseipeiihmtegrelvipcrvtspnitvtlkkfpldtlipdgkriiwds
rkgfiisnatykeiglltceatvnghlyktnylthrqt
Sequence, based on observed residues (ATOM records): (download)
>2xacX (X:)
grpfvemyseipeiihmtegrelvipcrvtspnitvtlkkfpldtlipdgkriiwdsrkg
fiisnatykeiglltceatvnghlyktnylthrqt