PDB entry 2xac

View 2xac on RCSB PDB site
Description: structural insights into the binding of vegf-b by vegfr-1d2: recognition and specificity
Class: transferase/signaling protein
Keywords: transferase-signaling protein complex, angiogenesis, cysteine-knot protein, mitogen, transferase, signaling protein
Deposited on 2010-03-30, released 2010-05-19
The last revision prior to the SCOPe 2.04 freeze date was dated 2010-08-04, with a file datestamp of 2010-07-30.
Experiment type: XRAY
Resolution: 2.71 Å
R-factor: 0.286
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: vascular endothelial growth factor b
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2xaca_
  • Chain 'B':
    Compound: vascular endothelial growth factor b
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2xacb_
  • Chain 'C':
    Compound: vascular endothelial growth factor receptor 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2xacc_
  • Chain 'X':
    Compound: vascular endothelial growth factor receptor 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2xacx_
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2xacA (A:)
    hqrkvvswidvytratcqprevvvpltvelmgtvakqlvpscvtvqrcggccpddglecv
    ptgqhqvrmqilmirypssqlgemsleehsqcecrpkkk
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2xacB (B:)
    hqrkvvswidvytratcqprevvvpltvelmgtvakqlvpscvtvqrcggccpddglecv
    ptgqhqvrmqilmirypssqlgemsleehsqcecrpkkk
    

    Sequence, based on observed residues (ATOM records): (download)
    >2xacB (B:)
    qrkvvswidvytratcqprevvvpltvelmgtvakqlvpscvtvqrcggccpddglecvp
    tgqhqvrmqilmirypssqlgemsleehsqcecrpkkk
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2xacC (C:)
    sdtgrpfvemyseipeiihmtegrelvipcrvtspnitvtlkkfpldtlipdgkriiwds
    rkgfiisnatykeiglltceatvnghlyktnylthrqt
    

  • Chain 'X':
    Sequence, based on SEQRES records: (download)
    >2xacX (X:)
    sdtgrpfvemyseipeiihmtegrelvipcrvtspnitvtlkkfpldtlipdgkriiwds
    rkgfiisnatykeiglltceatvnghlyktnylthrqt
    

    Sequence, based on observed residues (ATOM records): (download)
    >2xacX (X:)
    grpfvemyseipeiihmtegrelvipcrvtspnitvtlkkfpldtlipdgkriiwdsrkg
    fiisnatykeiglltceatvnghlyktnylthrqt