PDB entry 2xa0

View 2xa0 on RCSB PDB site
Description: crystal structure of bcl-2 in complex with a bax bh3 peptide
Deposited on 2010-03-25, released 2010-11-24
The last revision was dated 2011-06-01, with a file datestamp of 2011-05-27.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.2223
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Apoptosis regulator Bcl-2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Apoptosis regulator Bcl-2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Apoptosis regulator BAX
    Species: MUS MUSCULUS, synthetic [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Apoptosis regulator BAX
    Species: MUS MUSCULUS, synthetic [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2xa0A (A:)
mahagrtgydnreivmkyihyklsqrgyewdagdvgaappgaapapgifssqpghtphpa
asrdpvartsplqtpaapgaaagpalspvppvvhltlrqagddfsrryrrdfaemssqlh
ltpftargrfatvveelfrdgvnwgrivaffefggvmcvesvnremsplvdnialwmtey
lnrhlhtwiqdnggwdafvelygpsmr

    Sequence, based on observed residues (ATOM records):
    >2xa0A (A:)
dnreivmkyihyklsqrgyewdvvhltlrqagddfsrryrrdfaemssqlhltpftargr
fatvveelfrdgvnwgrivaffefggvmcvesvnremsplvdnialwmteylnrhlhtwi
qdnggwdafvelygpsm

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2xa0B (B:)
mahagrtgydnreivmkyihyklsqrgyewdagdvgaappgaapapgifssqpghtphpa
asrdpvartsplqtpaapgaaagpalspvppvvhltlrqagddfsrryrrdfaemssqlh
ltpftargrfatvveelfrdgvnwgrivaffefggvmcvesvnremsplvdnialwmtey
lnrhlhtwiqdnggwdafvelygpsmr

    Sequence, based on observed residues (ATOM records):
    >2xa0B (B:)
dnreivmkyihyklsqrgyewdvvhltlrqagddfsrryrrdfaemssqlhltpftargr
fatvveelfrdgvnwgrivaffefggvmcvesvnremsplvdnialwmteylnrhlhtwi
qdnggwdafvelygpsm

  • Chain 'C':
    Sequence, based on SEQRES records:
    >2xa0C (C:)
qdastkklseclrrigdeldsnmelqrmiad

    Sequence, based on observed residues (ATOM records):
    >2xa0C (C:)
kklseclrrigdeldsnmelqrmiad

  • Chain 'D':
    Sequence, based on SEQRES records:
    >2xa0D (D:)
qdastkklseclrrigdeldsnmelqrmiad

    Sequence, based on observed residues (ATOM records):
    >2xa0D (D:)
kklseclrrigdeldsnmelqrmiad