PDB entry 2x7e

View 2x7e on RCSB PDB site
Description: crystal structure of human kinesin eg5 in complex with (r)-fluorastrol
Class: cell cycle
Keywords: microtubule, ATP-binding, motor protein, cell division, mitosis, inhibitor, cell cycle, nucleotide-binding, ksp
Deposited on 2010-02-26, released 2010-07-14
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-09-21, with a file datestamp of 2011-09-16.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.19983
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Kinesin-like protein KIF11
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2x7ea_
  • Chain 'B':
    Compound: Kinesin-like protein KIF11
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2x7eb_
  • Heterogens: ADP, MG, X7E, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2x7eA (A:)
masqpnssakkkeekgkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladk
ssrktytfdmvfgastkqidvyrsvvcpildevimgynctifaygqtgtgktftmegers
pneeytweedplagiiprtlhqifekltdngtefsvkvslleiyneelfdllnpssdvse
rlqmfddprnkrgviikgleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfs
vtihmkettidgeelvkigklnlvdlagsenigrsgavdkrareagninqslltlgrvit
alvertphvpyreskltrilqdslggrtrtsiiatispaslnleetlstleyahraknil
nkpevnqk

    Sequence, based on observed residues (ATOM records): (download) 
    >2x7eA (A:)
kniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfdmvfgast
kqidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagii
prtlhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgvii
kgleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkettidgeelv
kigklnlvdlagsenninqslltlgrvitalvertphvpyreskltrilqdslggrtrts
iiatispaslnleetlstleyahraknilnkpe

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2x7eB (B:)
masqpnssakkkeekgkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladk
ssrktytfdmvfgastkqidvyrsvvcpildevimgynctifaygqtgtgktftmegers
pneeytweedplagiiprtlhqifekltdngtefsvkvslleiyneelfdllnpssdvse
rlqmfddprnkrgviikgleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfs
vtihmkettidgeelvkigklnlvdlagsenigrsgavdkrareagninqslltlgrvit
alvertphvpyreskltrilqdslggrtrtsiiatispaslnleetlstleyahraknil
nkpevnqk

    Sequence, based on observed residues (ATOM records): (download) 
    >2x7eB (B:)
kniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfdmvfgast
kqidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagii
prtlhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgvii
kgleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkettidgeelv
kigklnlvdlagsenninqslltlgrvitalvertphvpyreskltrilqdslggrtrts
iiatispaslnleetlstleyahraknilnkpevn