PDB entry 2x70

View 2x70 on RCSB PDB site
Description: Crystal structure of MHC CLass I HLA-A2.1 bound to a photocleavable peptide
Class: immune system
Keywords: immune system, amyloid, immunoglobulin domain, immune response, host-virus interaction
Deposited on 2010-02-22, released 2010-12-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-04-24, with a file datestamp of 2019-04-19.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla class I histocompatibility antigen, a-2.1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • expression tag (0)
    Domains in SCOPe 2.08: d2x70b1, d2x70b2
  • Chain 'C':
    Compound: hla-a2.1-restricted influenza a matrix epitope
    Species: Influenza A virus, synthetic [TaxId:11320]
    Database cross-references and differences (RAF-indexed):
    • PDB 2X70 (0-8)
  • Chain 'D':
    Compound: hla class I histocompatibility antigen, a-2.1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • expression tag (0)
    Domains in SCOPe 2.08: d2x70e1, d2x70e2
  • Chain 'F':
    Compound: hla-a2.1-restricted influenza a matrix epitope
    Species: Influenza A virus, synthetic [TaxId:11320]
    Database cross-references and differences (RAF-indexed):
    • PDB 2X70 (0-8)
  • Heterogens: GOL, MES, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2x70B (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2x70E (E:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'F':
    No sequence available.