PDB entry 2x6u
View 2x6u on RCSB PDB site
Description: crystal structure of human tbx5 in the DNA-free form
Class: transcription
Keywords: developmental protein, DNA-binding, holt-oram-syndrome, ig-fold, nuclear protein, repressor, tbx3, transcription, transcription regulation
Deposited on
2010-02-22, released
2010-04-28
The last revision prior to the SCOPe 2.08 freeze date was dated
2010-11-24, with a file datestamp of
2010-11-19.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.2131
AEROSPACI score: 0.47
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: t-box transcription factor tbx5
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2x6ua_ - Heterogens: PE4, MG, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2x6uA (A:)
gamegikvflherelwlkfhevgtemiitkagrrmfpsykvkvtglnpktkyillmdivp
addhrykfadnkwsvtgkaepampgrlyvhpdspatgahwmrqlvsfqklkltnnhldpf
ghiilnsmhkyqprlhivkadenngfgskntafcthvfpetafiavtsyqnhkitqlkie
nnpfakgfrgsddmelhrmsrmq
Sequence, based on observed residues (ATOM records): (download)
>2x6uA (A:)
egikvflherelwlkfhevgtemiitkagrrmfpsykvkvtglnpktkyillmdivpadd
hrykfadnkwsvtgkaeparlyvhpdspatgahwmrqlvsfqklkltnnhldpfghiiln
smhkyqprlhivkadenngfgskntafcthvfpetafiavtsyqnhkitqlkienn