PDB entry 2x5w

View 2x5w on RCSB PDB site
Description: X-ray structure of Mycobacterium tuberculosis cytochrome P450 CYP125 in complex with substrate cholest-4-en-3-one
Class: oxidoreductase
Keywords: cholesterol degradation, metal-binding, oxidoreductase
Deposited on 2010-02-10, released 2010-06-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-04-03, with a file datestamp of 2019-03-29.
Experiment type: XRAY
Resolution: 1.58 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: putative cytochrome p450 125
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2x5wa_
  • Heterogens: SO4, K2B, EDO, HEM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2x5wA (A:)
mhhhhhhmswnhqsveiavrrttvpspnlppgfdftdpaiyaerlpvaefaelrsaapiw
wngqdpgkgggfhdggfwaitklndvkeisrhsdvfssyengviprfkndiaredievqr
fvmlnmdaphhtrlrkiisrgftpravgrlhdelqeraqkiaaeaaaagsgdfveqvsce
lplqaiagllgvpqedrgklfhwsnemtgnedpeyahidpkassaeligyamkmaeekak
npaddivtqliqadidgeklsddefgffvvmlavagnettrnsitqgmmafaehpdqwel
ykkvrpetaadeivrwatpvtafqrtalrdyelsgvqikkgqrvvmfyrsanfdeevfqd
pftfnilrnpnphvgfggtgahyciganlarmtinlifnavadhmpdlkpisaperlrsg
wlngikhwqvdytgrcpvah

    Sequence, based on observed residues (ATOM records): (download) 
    >2x5wA (A:)
spnlppgfdftdpaiyaerlpvaefaelrsaapiwwngqdpgkgggfhdggfwaitklnd
vkeisrhsdvfssyengviprfkndiaredievqrfvmlnmdaphhtrlrkiisrgftpr
avgrlhdelqeraqkiaaeaaaagsgdfveqvscelplqaiagllgvpqedrgklfhwsn
emtgnedpeyahidpkassaeligyamkmaeekaknpaddivtqliqadidgeklsddef
gffvvmlavagnettrnsitqgmmafaehpdqwelykkvrpetaadeivrwatpvtafqr
talrdyelsgvqikkgqrvvmfyrsanfdeevfqdpftfnilrnpnphvgfggtgahyci
ganlarmtinlifnavadhmpdlkpisaperlrsgwlngikhwqvdytg