PDB entry 2x50

View 2x50 on RCSB PDB site
Description: Crystal structure of Trypanothione reductase from Leishmania infantum in complex with NADPH and silver
Deposited on 2010-02-03, released 2011-01-12
The last revision was dated 2014-06-18, with a file datestamp of 2014-06-13.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: 0.23105
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: trypanothione reductase
    Species: Leishmania infantum [TaxId:5671]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: trypanothione reductase
    Species: Leishmania infantum [TaxId:5671]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: FAD, NDP, AG, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >2x50A (A:)
mgsshhhhhhssglvprgshmsraydlvvlgagsggleagwnaavthkkkvavvdvqath
gpplfaalggtcvnvgcvpkklmvtgaqymdliresggfgwemdreslcpnwktliaakn
kvvnsinesyksmfadteglsfhmgfgalqdahtvvvrksedphsdvletldteyiliat
gswptrlgvpgdefcitsneafyledapkrmlcvgggyiavefagifngykpcggyvdlc
yrgdlilrgfdtevrksltkqlgangirvrtnlnptkitknedgsnhvhfndgteedydq
vmlaigrvprsqalqldkagvrtgkngavqvdaysktsvdniyaigdvtnrvmltpvain
egaafvetvfggkpratdhtkvacavfsippigtcgmteeeaaknyetvavyassftplm
hnisgskhkefmiriitnesngevlgvhmlgdsapeiiqsvgicmkmgakisdfhstigv
hptsaeelcsmrtpayfyesgkrveklssn

    Sequence, based on observed residues (ATOM records):
    >2x50A (A:)
sraydlvvlgagsggleagwnaavthkkkvavvdvqathgpplfaalggtcvnvgcvpkk
lmvtgaqymdliresggfgwemdreslcpnwktliaaknkvvnsinesyksmfadtegls
fhmgfgalqdahtvvvrksedphsdvletldteyiliatgswptrlgvpgdefcitsnea
fyledapkrmlcvgggyiavefagifngykpcggyvdlcyrgdlilrgfdtevrksltkq
lgangirvrtnlnptkitknedgsnhvhfndgteedydqvmlaigrvprsqalqldkagv
rtgkngavqvdaysktsvdniyaigdvtnrvmltpvainegaafvetvfggkpratdhtk
vacavfsippigtcgmteeeaaknyetvavyassftplmhnisgskhkefmiriitnesn
gevlgvhmlgdsapeiiqsvgicmkmgakisdfhstigvhptsaeelcsmrtpayfyesg
krvek

  • Chain 'B':
    Sequence, based on SEQRES records:
    >2x50B (B:)
mgsshhhhhhssglvprgshmsraydlvvlgagsggleagwnaavthkkkvavvdvqath
gpplfaalggtcvnvgcvpkklmvtgaqymdliresggfgwemdreslcpnwktliaakn
kvvnsinesyksmfadteglsfhmgfgalqdahtvvvrksedphsdvletldteyiliat
gswptrlgvpgdefcitsneafyledapkrmlcvgggyiavefagifngykpcggyvdlc
yrgdlilrgfdtevrksltkqlgangirvrtnlnptkitknedgsnhvhfndgteedydq
vmlaigrvprsqalqldkagvrtgkngavqvdaysktsvdniyaigdvtnrvmltpvain
egaafvetvfggkpratdhtkvacavfsippigtcgmteeeaaknyetvavyassftplm
hnisgskhkefmiriitnesngevlgvhmlgdsapeiiqsvgicmkmgakisdfhstigv
hptsaeelcsmrtpayfyesgkrveklssn

    Sequence, based on observed residues (ATOM records):
    >2x50B (B:)
sraydlvvlgagsggleagwnaavthkkkvavvdvqathgpplfaalggtcvnvgcvpkk
lmvtgaqymdliresggfgwemdreslcpnwktliaaknkvvnsinesyksmfadtegls
fhmgfgalqdahtvvvrksedphsdvletldteyiliatgswptrlgvpgdefcitsnea
fyledapkrmlcvgggyiavefagifngykpcggyvdlcyrgdlilrgfdtevrksltkq
lgangirvrtnlnptkitknedgsnhvhfndgteedydqvmlaigrvprsqalqldkagv
rtgkngavqvdaysktsvdniyaigdvtnrvmltpvainegaafvetvfggkpratdhtk
vacavfsippigtcgmteeeaaknyetvavyassftplmhnisgskhkefmiriitnesn
gevlgvhmlgdsapeiiqsvgicmkmgakisdfhstigvhptsaeelcsmrtpayfyesg
krvekls