PDB entry 2x4z

View 2x4z on RCSB PDB site
Description: Crystal Structure of the Human p21-Activated Kinase 4 in Complex with PF-03758309
Class: transferase
Keywords: transferase, nucleotide-binding ATP-binding, phosphoprotein
Deposited on 2010-02-03, released 2010-05-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-01-23, with a file datestamp of 2019-01-18.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine/threonine-protein kinase pak 4
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O96013
      • engineered mutation (3)
    Domains in SCOPe 2.08: d2x4za1, d2x4za2
  • Heterogens: GOL, 7KC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2x4zA (A:)
gshmsheqfraalqlvvdpgdprsyldnfikigegstgivciatvrssgklvavkkmdlr
kqqrrellfnevvimrdyqhenvvemynsylvgdelwvvmefleggaltdivthtrmnee
qiaavclavlqalsvlhaqgvihrdiksdsillthdgrvklsdfgfcaqvskevprrksl
vgtpywmapelisrlpygpevdiwslgimviemvdgeppyfnepplkamkmirdnlpprl
knlhkvspslkgfldrllvrdpaqrataaellkhpflakagppasivplmrqnrtr

    Sequence, based on observed residues (ATOM records): (download) 
    >2x4zA (A:)
msheqfraalqlvvdpgdprsyldnfikigegstgivciatvrssgklvavkkmdlrkqq
rrellfnevvimrdyqhenvvemynsylvgdelwvvmefleggaltdivthtrmneeqia
avclavlqalsvlhaqgvihrdiksdsillthdgrvklsdfgfcaqvskevprrkslvgt
pywmapelisrlpygpevdiwslgimviemvdgeppyfnepplkamkmirdnlpprlknl
hkvspslkgfldrllvrdpaqrataaellkhpflakagppasivplmrqnrt