PDB entry 2x4r

View 2x4r on RCSB PDB site
Description: crystal structure of MHC class I hla-a2.1 bound to cytomegalovirus (cmv) pp65 epitope
Class: immune system
Keywords: immunoglobulin domain, host-virus interaction, glycation, amyloidosis, amyloid, photocleavable peptide, immune response, immune system
Deposited on 2010-02-02, released 2010-03-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-03-02, with a file datestamp of 2010-02-26.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.142
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: hla class I histocompatibility antigen, a-2.1
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01892 (0-274)
• Chain 'B':
  Compound: Beta-2-microglobulin
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 2X4R (0-0)
  • Uniprot P61769 (1-99)
  Domains in SCOPe 2.08: d2x4rb1, d2x4rb2
• Chain 'C':
  Compound: 65 kda phosphoprotein
  Species: HUMAN HERPESVIRUS 5, synthetic [TaxId:10359]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P06725 (0-8)
• Chain 'D':
  Compound: hla class I histocompatibility antigen, a-2.1
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01892 (0-274)
• Chain 'E':
  Compound: Beta-2-microglobulin
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 2X4R (0-0)
  • Uniprot P61769 (1-99)
  Domains in SCOPe 2.08: d2x4re1, d2x4re2
• Chain 'F':
  Compound: 65 kda phosphoprotein
  Species: HUMAN HERPESVIRUS 5, synthetic [TaxId:10359]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P06725 (0-8)
• Heterogens: GOL, HOH

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2x4rB (B:)
  miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
  wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
  

  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'D':
  No sequence available.
  
  
• Chain 'E':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2x4rE (E:)
  miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
  wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
  

  
  
• Chain 'F':
  No sequence available.