PDB entry 2x4p

View 2x4p on RCSB PDB site
Description: Crystal structure of MHC CLass I HLA-A2.1 bound to a photocleavable peptide
Class: immune system
Keywords: glycoprotein, immune system, immunoglobulin domain, matrix (m1)
Deposited on 2010-02-02, released 2010-03-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-04-24, with a file datestamp of 2019-04-19.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla class I histocompatibility antigen, a-2.1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2X4P (0-0)
    • Uniprot P61769 (1-99)
    Domains in SCOPe 2.08: d2x4pb1, d2x4pb2
  • Chain 'C':
    Compound: hla-a2.1-restricted influenza a matrix epitope
    Species: Influenza A virus, synthetic [TaxId:11320]
    Database cross-references and differences (RAF-indexed):
    • PDB 2X4P (0-8)
  • Chain 'D':
    Compound: hla class I histocompatibility antigen, a-2.1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2X4P (0-0)
    • Uniprot P61769 (1-99)
    Domains in SCOPe 2.08: d2x4pe1, d2x4pe2
  • Chain 'F':
    Compound: hla-a2.1-restricted influenza a matrix epitope
    Species: Influenza A virus, synthetic [TaxId:11320]
    Database cross-references and differences (RAF-indexed):
    • PDB 2X4P (0-8)
  • Heterogens: GOL, MES, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2x4pB (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2x4pE (E:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'F':
    No sequence available.