PDB entry 2x4f

View 2x4f on RCSB PDB site
Description: The Crystal Structure of the human myosin light chain kinase LOC340156.
Class: transferase
Keywords: lung, kinase, myosin, breast cancer, transferase
Deposited on 2010-01-29, released 2010-02-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-24, with a file datestamp of 2018-01-19.
Experiment type: XRAY
Resolution: 2.67 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: myosin light chain kinase family member 4
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2X4F
      • conflict (355)
    • Uniprot Q86YV6
    Domains in SCOPe 2.08: d2x4fa_
  • Chain 'B':
    Compound: myosin light chain kinase family member 4
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2x4fb_
  • Heterogens: 16X, SO4, 1PE, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2x4fA (A:)
mghhhhhhssgvdlgtenlyfqsmknsgdqdsrsghneakevwsnadltermpvkskrts
alavdipappapfdhrivtakqgavnsfytvskteilgggrfgqvhkceetatglklaak
iiktrgmkdkeevkneisvmnqldhanliqlydafeskndivlvmeyvdggelfdriide
synlteldtilfmkqicegirhmhqmyilhldlkpenilcvnrdakqikiidfglarryk
preklkvnfgtpeflapevvnydfvsfptdmwsvgviaymllsglspflgdndaetlnni
lacrwdledeefqdiseeakefiskllikekswrisasealkhpwlsdhklhsrlsaqkk
knrgsdaqdfvtk

    Sequence, based on observed residues (ATOM records): (download) 
    >2x4fA (A:)
dipappapfdhrivtakqgavnsfytvskteilgqvhkceetatglklaakiiktrgmkd
keevkneisvmnqldhanliqlydafeskndivlvmeyvdggelfdriidesynlteldt
ilfmkqicegirhmhqmyilhldlkpenilcvnrdakqikiidfglarrykpreklkvnf
gtpeflapevvnydfvsfptdmwsvgviaymllsglspflgdndaetlnnilacrwdled
eefqdiseeakefiskllikekswrisasealkhpwlsdhklhsrlsaq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2x4fB (B:)
mghhhhhhssgvdlgtenlyfqsmknsgdqdsrsghneakevwsnadltermpvkskrts
alavdipappapfdhrivtakqgavnsfytvskteilgggrfgqvhkceetatglklaak
iiktrgmkdkeevkneisvmnqldhanliqlydafeskndivlvmeyvdggelfdriide
synlteldtilfmkqicegirhmhqmyilhldlkpenilcvnrdakqikiidfglarryk
preklkvnfgtpeflapevvnydfvsfptdmwsvgviaymllsglspflgdndaetlnni
lacrwdledeefqdiseeakefiskllikekswrisasealkhpwlsdhklhsrlsaqkk
knrgsdaqdfvtk

    Sequence, based on observed residues (ATOM records): (download) 
    >2x4fB (B:)
ipappapfdhrivtakqgavnsfytvskteilggggqvhkceetatglklaakiiktrgm
kdkeevkneisvmnqldhanliqlydafeskndivlvmeyvdggelfdriidesynltel
dtilfmkqicegirhmhqmyilhldlkpenilcvnrdakqikiidfglarrykpreklkv
nfgtpeflapevvnydfvsfptdmwsvgviaymllsglspflgdndaetlnnilacrwdl
edeefqdiseeakefiskllikekswrisasealkhpwlsdhklhsrl