PDB entry 2x1l

View 2x1l on RCSB PDB site
Description: Crystal structure of Mycobacterium smegmatis methionyl-tRNA synthetase in complex with methionine and adenosine
Class: ligase
Keywords: nucleotide-binding, protein biosynthesis, ligase, aminoacyl-tRNA synthetase
Deposited on 2009-12-31, released 2010-07-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-01-30, with a file datestamp of 2019-01-25.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Methionyl-tRNA synthetase
    Species: MYCOBACTERIUM SMEGMATIS [TaxId:246196]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2x1la1, d2x1la2
  • Chain 'B':
    Compound: Methionyl-tRNA synthetase
    Species: MYCOBACTERIUM SMEGMATIS [TaxId:246196]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2x1lb1, d2x1lb2
  • Chain 'C':
    Compound: Methionyl-tRNA synthetase
    Species: MYCOBACTERIUM SMEGMATIS [TaxId:246196]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2x1lc1, d2x1lc2
  • Heterogens: MET, ADN, CXS, 2HP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2x1lA (A:)
    mahhhhhhggsepfyittaiaypngvphighayeyiatdaiarfkrldgydvryltgtdv
    hgqkmaetaakegipaaelarrnsdvfqrlqeklnisfdrfirtsdadhyeaskaiwkrm
    adagdiyldaykgwysirderfftenetteqpdgtriatetgapvtwteeqtyffrlsay
    tdrllalyeehpefigpdarrneivsfvsgglkdlsisrttfdwgvpvpdhpdhvmyvwv
    daltnyltgvgfpdtesesfrrywpadlhmigkdiirfhtvywpaflmsaglplpkrifa
    hgwllnrgekmsksignvvdpvnlvdtfgldqvryfllrevpfgqdgsynedaiigrvna
    dlanelgnlaqrslsmvaknlgaavpdpgeftdedtallaaadallervrehfdvpamhl
    aleaiwsvlgaanryfsaqepwvlrksdaaedqqrfrtvlyttlevvriaslllqpvmpe
    staklldllgqptderdfsaianrikpgtslpapsgifpryqnd
    

    Sequence, based on observed residues (ATOM records): (download)
    >2x1lA (A:)
    sepfyittaiaypngvphighayeyiatdaiarfkrldgydvryltgtdvhgqkmaetaa
    kegipaaelarrnsdvfqrlqeklnisfdrfirtsdadhyeaskaiwkrmadagdiylda
    ykgwysirderfftenetteqpdgtriatetgapvtwteeqtyffrlsaytdrllalyee
    hpefigpdarrneivsfvsgglkdlsisrttfdwgvpvpdhpdhvmyvwvdaltnyltgv
    gfpdtesesfrrywpadlhmigkdiirfhtvywpaflmsaglplpkrifahgwllnrgek
    msksignvvdpvnlvdtfgldqvryfllrevpfgqdgsynedaiigrvnadlanelgnla
    qrslsmvaknlgaavpdpgeftdedtallaaadallervrehfdvpamhlaleaiwsvlg
    aanryfsaqepwvlrksdaaedqqrfrtvlyttlevvriaslllqpvmpestaklldllg
    qptderdfsaianrikpgtslpapsgifpry
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2x1lB (B:)
    mahhhhhhggsepfyittaiaypngvphighayeyiatdaiarfkrldgydvryltgtdv
    hgqkmaetaakegipaaelarrnsdvfqrlqeklnisfdrfirtsdadhyeaskaiwkrm
    adagdiyldaykgwysirderfftenetteqpdgtriatetgapvtwteeqtyffrlsay
    tdrllalyeehpefigpdarrneivsfvsgglkdlsisrttfdwgvpvpdhpdhvmyvwv
    daltnyltgvgfpdtesesfrrywpadlhmigkdiirfhtvywpaflmsaglplpkrifa
    hgwllnrgekmsksignvvdpvnlvdtfgldqvryfllrevpfgqdgsynedaiigrvna
    dlanelgnlaqrslsmvaknlgaavpdpgeftdedtallaaadallervrehfdvpamhl
    aleaiwsvlgaanryfsaqepwvlrksdaaedqqrfrtvlyttlevvriaslllqpvmpe
    staklldllgqptderdfsaianrikpgtslpapsgifpryqnd
    

    Sequence, based on observed residues (ATOM records): (download)
    >2x1lB (B:)
    sepfyittaiaypngvphighayeyiatdaiarfkrldgydvryltgtdvhgqkmaetaa
    kegipaaelarrnsdvfqrlqeklnisfdrfirtsdadhyeaskaiwkrmadagdiylda
    ykeqtyffrlsaytdrllalyeehpefigpdarrneivsfvsgglkdlsisrttfdwgvp
    vpdhpdhvmyvwvdaltnyltgvgfpdtesesfrrywpadlhmigkdiirfhtvywpafl
    msaglplpkrifahgwllnrgekmsksignvvdpvnlvdtfgldqvryfllrevpfgqdg
    synedaiigrvnadlanelgnlaqrslsmvaknlgaavpdpgeftdedtallaaadalle
    rvrehfdvpamhlaleaiwsvlgaanryfsaqepwvlrksdaaedqqrfrtvlyttlevv
    riaslllqpvmpestaklldllgqptderdfsaianrikpgtslpapsgifpry
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2x1lC (C:)
    mahhhhhhggsepfyittaiaypngvphighayeyiatdaiarfkrldgydvryltgtdv
    hgqkmaetaakegipaaelarrnsdvfqrlqeklnisfdrfirtsdadhyeaskaiwkrm
    adagdiyldaykgwysirderfftenetteqpdgtriatetgapvtwteeqtyffrlsay
    tdrllalyeehpefigpdarrneivsfvsgglkdlsisrttfdwgvpvpdhpdhvmyvwv
    daltnyltgvgfpdtesesfrrywpadlhmigkdiirfhtvywpaflmsaglplpkrifa
    hgwllnrgekmsksignvvdpvnlvdtfgldqvryfllrevpfgqdgsynedaiigrvna
    dlanelgnlaqrslsmvaknlgaavpdpgeftdedtallaaadallervrehfdvpamhl
    aleaiwsvlgaanryfsaqepwvlrksdaaedqqrfrtvlyttlevvriaslllqpvmpe
    staklldllgqptderdfsaianrikpgtslpapsgifpryqnd
    

    Sequence, based on observed residues (ATOM records): (download)
    >2x1lC (C:)
    sepfyittaiaypngvphighayeyiatdaiarfkrldgydvryltgtdvhgqkmaetaa
    kegipaaelarrnsdvfqrlqeklnisfdrfirtsdadhyeaskaiwkrmadagdiylda
    yteeqtyffrlsaytdrllalyeehpefigpdarrneivsfvsgglkdlsisrttfdwgv
    pvpdhpdhvmyvwvdaltnyltgvgfpdtesesfrrywpadlhmigkdiirfhtvywpaf
    lmsaglplpkrifahgwllnrgekmsksignvvdpvnlvdtfgldqvryfllrevpfgqd
    gsynedaiigrvnadlanelgnlaqrslsmvaknlgaavpdpgeftdedtallaaadall
    ervrehfdvpamhlaleaiwsvlgaanryfsaqepwvlrksdaaedqqrfrtvlyttlev
    vriaslllqpvmpestaklldllgqptderdfsaianrikpgtslpapsgifpryq